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Mouse Anti-EXOC3 Recombinant Antibody (CBXS-5982) (CBMAB-S0829-CQ)

This product is a mouse antibody that recognizes EXOC3. The antibody CBXS-5982 can be used for immunoassay techniques such as: WB, IHC, IF, IHC-P.
See all EXOC3 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat, Pig, Cattle, Dog, Chicken, Hamster, Monkey, Rabbit, Sheep
Clone
CBXS-5982
Antibody Isotype
IgG2a
Application
WB, IHC, IF, IHC-P

Basic Information

Immunogen
Recombinant rat Sec6
Specificity
Human, Mouse, Rat, Pig, Cattle, Dog, Chicken, Hamster, Monkey, Rabbit, Sheep
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
exocyst complex component 3
Introduction
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Entrez Gene ID
Human11336
Mouse211446
Rat252881
Pig100624948
Cattle513138
Dog478633
Chicken420987
Hamster101828863
Monkey708422
Rabbit100356252
Sheep101103266
UniProt ID
HumanO60645
MouseQ6KAR6
RatQ62825
PigA0A480TWJ1
CattleQ0V8C2
DogF1PX56
ChickenF1NHD9
HamsterA0A1U7QDT1
MonkeyA0A2K5UMY4
RabbitG1T0H9
SheepW5Q2L6
Alternative Names
Exocyst Complex Component 3; Exocyst Complex Component Sec6; SEC6L1; SEC6; SEC6-Like 1 (S. Cerevisiae); Sec 6 Homolog; SEC6-Like 1; Sec6p;
Research Area
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Biological Process
Exocyst localization Source: GO_Central
Exocytosis Source: GO_Central
Protein transport Source: UniProtKB-KW
Cellular Location
Cytoplasm; Golgi apparatus; Perinuclear region; Growth cone; Midbody; Neuron projection. Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (PubMed:18756269).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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