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Mouse Anti-FGFR1OP2 Recombinant Antibody (2G4) (CBMAB-A2953-LY)

The product is antibody recognizes FGFR1OP2. The antibody 2G4 immunoassay techniques such as: WB, ELISA.
See all FGFR1OP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2G4
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
FGFR1OP2 (NP_056448, 62 a.a. ~ 169 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
FGFR1 oncogene partner 2
Entrez Gene ID
26127
UniProt ID
Q9NVK5
Alternative Names
DKFZp564O1863; HSPC123-like
Function
May be involved in wound healing pathway.
Biological Process
Response to wounding Source: GO_Central
Wound healing Source: Ensembl
Cellular Location
Cytoplasm
Involvement in disease
A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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