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Rabbit Anti-MAP1A Monoclonal Antibody (EPR18994) (CBMAB-1383-YC)

Provided herein is a rabbit monoclonal antibody against Mouse MAP1A. The antibody, clone EPR18994, can be used for immunoassay techniques, such as FC, ICC, IF and WB.
See all MAP1A antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat
Clone
EPR18994
Antibody Isotype
IgG
Application
FC, ICC, IF, WB

Basic Information

Immunogen
Recombinant fragment within Mouse MAP1A aa 2550-2700.
Specificity
Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MICROTUBULE ASSOCIATED PROTEIN 1A
Introduction
MAP1A belongs to the microtubule-associated protein family. MAP1A is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of MAP1A is almost exclusively in the brain. It is suggested that MAP1A plays a role in early events of spinal cord development.
Entrez Gene ID
Mouse17754
Rat25152
UniProt ID
MouseQ9QYR6
RatP34926
Alternative Names
Mtap1; moth1; Mtap-1; Mtap1a; AI853608; 6330416M19Rik
Function
Structural protein involved in the filamentous cross-bridging between microtubules and other skeletal elements.
Biological Process
Anterograde axonal protein transportISS:ARUK-UCL
Associative learningISS:ARUK-UCL
AxonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Dendrite developmentManual Assertion Based On ExperimentIBA:GO_Central
MemoryISS:ARUK-UCL
Microtubule cytoskeleton organizationISS:ARUK-UCL
Negative regulation of proteasomal ubiquitin-dependent protein catabolic processISS:ARUK-UCL
Negative regulation of protein localization to microtubuleISS:ARUK-UCL
Neuron cellular homeostasisISS:ARUK-UCL
Neuron projection maintenanceISS:ARUK-UCL
Positive regulation of protein localizationISS:ARUK-UCL
Positive regulation of protein localization to cell surfaceISS:ARUK-UCL
Regulation of microtubule depolymerizationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of synaptic plasticityISS:ARUK-UCL
Retrograde axonal protein transportISS:ARUK-UCL
Voluntary musculoskeletal movementISS:ARUK-UCL
Cellular Location
Cytoplasm, cytoskeleton
PTM
Phosphorylated by CSNK1D.
LC2 is generated from MAP1A by proteolytic processing.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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