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Mouse Anti-SLC31A1 Recombinant Antibody (CBWJC-3400) (CBMAB-C4617WJ)

This product is a Mouse antibody that recognizes SLC31A1. This antibody CBWJC-3400 can be used for immunoassay techniques such as: ELISA, FC, ICC, IHC-P, WB.
See all SLC31A1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rabbit, Cattle
Clone
CBWJC-3400
Antibody Isotype
IgG2a
Application
ELISA, FC, ICC, IHC-P, WB

Basic Information

Immunogen
Synthetic peptide derived from sequence situated on the extra-cellular domain of human calcitonin receptor
Specificity
Human, Rabbit, Cattle
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Preservative
0.09% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SLC31A1
Introduction
SLC31A1 (Solute Carrier Family 31 Member 1) is a Protein Coding gene. Diseases associated with SLC31A1 include Wilson Disease. Among its related pathways are Mineral absorption and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include copper ion transmembrane transporter activity. An important paralog of this gene is SLC31A2.
Entrez Gene ID
Human1317
Rabbit100349206
Cattle518976
UniProt ID
HumanO15431
RabbitG1SN32
CattleA6QR68
Alternative Names
CTR1; COPT1
Function
High-affinity, saturable copper transporter involved in dietary copper uptake.
Biological Process
Biological Process cellular copper ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process copper ion importIEA:Ensembl
Biological Process copper ion transportManual Assertion Based On ExperimentTAS:ProtInc
Biological Process establishment of localization in cellIEA:Ensembl
Cellular Location
Cell membrane
Localizes to the apical membrane in intestinal epithelial cells.
Topology
Extracellular: 1-61
Helical: 62-82
Cytoplasmic: 83-132
Helical: 133-153
Extracellular: 154-156
Helical: 157-177
Cytoplasmic: 178-190
PTM
O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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