Sign in or Register   Sign in or Register
  |  

Rat Anti-TUB Recombinant Antibody (CBMY-C0263) (CBMAB-V208-C0266-YY)

This product is rat antibody that recognizes TUB. The antibody CBMY-C0263 can be used for immunoassay techniques such as: ELISA, IHC-Fr, IP, RIA, WB
See all TUB antibodies

Summary

Host Animal
Rat
Specificity
Yeast
Clone
CBMY-C0263
Antibody Isotype
IgG2a
Application
ELISA, IHC-Fr, IP, RIA, WB

Basic Information

Specificity
Yeast
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Tubby Bipartite Transcription Factor
Function
Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity).
Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.
Biological Process
Biological Process intraciliary transport Source:MGI1 Publication
Biological Process phagocytosis, recognition Source:Ensembl
Biological Process photoreceptor cell maintenance Source:Ensembl
Biological Process positive regulation of phagocytosis Source:UniProtKB1 Publication
Biological Process protein localization to cilium Source:GO_Central1 Publication
Biological Process protein localization to photoreceptor outer segment Source:Ensembl
Biological Process receptor localization to non-motile cilium Source:Ensembl
Biological Process regulation of G protein-coupled receptor signaling pathway Source:Ensembl
Biological Process response to stimulus Source:UniProtKB-KW
Biological Process retina development in camera-type eye Source:Ensembl
Biological Process sensory perception of sound Source:Ensembl
Cellular Location
Cytoplasm
Nucleus
Secreted
Cell membrane
Binds phospholipid and is anchored to the plasma membrane through binding phosphatidylinositol 4,5-bisphosphate. Is released upon activation of phospholipase C. Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity).
Involvement in disease
Retinal dystrophy and obesity (RDOB):
A disease characterized by obesity, night blindness, decreased visual acuity, and electrophysiological features of a rod cone dystrophy.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rat Anti-TUB Recombinant Antibody (CBMY-C0263)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare