BAMBI

This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq]
Full Name
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
Function
Negatively regulates TGF-beta signaling.
Biological Process
Cell migration Source: BHF-UCL
Negative regulation of BMP signaling pathway Source: ARUK-UCL
Negative regulation of osteoblast differentiation Source: ARUK-UCL
Negative regulation of transforming growth factor beta receptor signaling pathway Source: BHF-UCL
Positive regulation of canonical Wnt signaling pathway Source: BHF-UCL
Positive regulation of cell population proliferation Source: BHF-UCL
Positive regulation of epithelial to mesenchymal transition Source: BHF-UCL
Positive regulation of protein binding Source: BHF-UCL
Positive regulation of transcription, DNA-templated Source: BHF-UCL
Regulation of cell shape Source: BHF-UCL
Transforming growth factor beta receptor signaling pathway Source: GO_Central
Cellular Location
Membrane
Topology
Extracellular: 21-152 aa
Helical: 153-173 aa
Cytoplasmic: 174-260 aa
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Anti-BAMBI antibodies

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Mouse Anti-BAMBI Recombinant Antibody (3C1-1D1) (CBMAB-A0706-LY)

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Target: BAMBI
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3C1-1D1
Application*: WB, E
Datasheet SDS

Mouse Anti-BAMBI Recombinant Antibody (CBYY-2032) (CBMAB-2381-YY)

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Target: BAMBI
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYY-2032
Application*: WB
Datasheet SDS

Mouse Anti-BAMBI Recombinant Antibody (CBYY-1680) (CBMAB-2029-YY)

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Target: BAMBI
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYY-1680
Application*: WB
Datasheet SDS

Mouse Anti-BAMBI Recombinant Antibody (CBYY-0185) (CBMAB-0186-YY)

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Target: BAMBI
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-0185
Application*: E
Datasheet SDS

Mouse Anti-BAMBI Recombinant Antibody (CBYY-0182) (CBMAB-0183-YY)

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Target: BAMBI
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0182
Application*: E
Datasheet SDS

Mouse Anti-BAMBI Recombinant Antibody (CBYY-0181) (CBMAB-0182-YY)

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Target: BAMBI
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0181
Application*: E
Datasheet SDS

Mouse Anti-BAMBI Recombinant Antibody (CBYY-0180) (CBMAB-0181-YY)

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Target: BAMBI
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-0180
Application*: WB, IP, E
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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