Human BAMBI ELISA Kit (V2LY-0626-LY2601)

Name: Human BAMBI ELISA Kit
SKU: V2LY-0626-LY2601
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.023 ng/mL

Detection Range

0.05-20 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Human

Assay Type

Sandwich

Reactivity

Human

Assay Time

1.5 h

Molecule Mass

29.1 kDa

Components

Pre-coated ELISA plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)

Function

Negatively regulates TGF-beta signaling.

Biological Process

Cell migration Source: BHF-UCL
Negative regulation of BMP signaling pathway Source: ARUK-UCL
Negative regulation of osteoblast differentiation Source: ARUK-UCL
Negative regulation of transforming growth factor beta receptor signaling pathway Source: BHF-UCL
Positive regulation of canonical Wnt signaling pathway Source: BHF-UCL
Positive regulation of cell population proliferation Source: BHF-UCL
Positive regulation of epithelial to mesenchymal transition Source: BHF-UCL
Positive regulation of protein binding Source: BHF-UCL
Positive regulation of transcription, DNA-templated Source: BHF-UCL
Regulation of cell shape Source: BHF-UCL
Transforming growth factor beta receptor signaling pathway Source: GO_Central

Cellular Location

Membrane

Topology

Extracellular: 21-152 aa
Helical: 153-173 aa
Cytoplasmic: 174-260 aa

Chen, X., Zhao, C., Xu, Y., Huang, K., Wang, Y., Wang, X., ... & Yu, T. (2021). Adipose-specific BMP and activin membrane-bound inhibitor (BAMBI) deletion promotes adipogenesis by accelerating ROS production. Journal of Biological Chemistry, 296.

Nangaku, M. (2020). Schlöndorff and Lee revealed crosstalk between glomerular cells and a role of BAMBI in diabetic kidney disease. Kidney International, 98(3), 539-541.

Alvarez, P., Augustín, J. J., Tamayo, E., Iglesias, M., Acinas, O., Mendiguren, M. A., ... & Merino, R. (2020). Therapeutic Effects of Anti–Bone Morphogenetic Protein and Activin Membrane‐Bound Inhibitor Treatment in Psoriasis and Arthritis. Arthritis & Rheumatology, 72(9), 1547-1558.

Yao, X., Yu, T., Xi, F., Xu, Y., Ma, L., Pan, X., ... & Xie, L. (2019). BAMBI shuttling between cytosol and membrane is required for skeletal muscle development and regeneration. Biochemical and biophysical research communications, 509(1), 125-132.

Wang, D., Chen, X., & Zhang, R. (2018). BAMBI promotes macrophage proliferation and differentiation in gliomas. Molecular medicine reports, 17(3), 3960-3966.

Hernandez, H., Millar, J. C., Curry, S. M., Clark, A. F., & McDowell, C. M. (2018). BMP and activin membrane bound inhibitor regulates the extracellular matrix in the trabecular meshwork. Investigative ophthalmology & visual science, 59(5), 2154-2166.

Yu, W., & Chai, H. (2017). Inhibition of BAMBI reduces the viability and motility of colon cancer via activating TGF‑β/Smad pathway in vitro and in vivo. Oncology letters, 14(4), 4793-4799.

Bai, L., Chu, G., Wang, W., Xiang, A., & Yang, G. (2017). BAMBI promotes porcine granulosa cell steroidogenesis involving TGF-β signaling. Theriogenology, 100, 24-31.

Wang, X., Li, M., Hu, M., Wei, P., & Zhu, W. (2017). BAMBI overexpression together with β-sitosterol ameliorates NSCLC via inhibiting autophagy and inactivating TGF-β/Smad2/3 pathway. Oncology reports, 37(5), 3046-3054.

Yang, Y., Guo, C., Liao, B., Cao, J., Liang, C., & He, X. (2017). BAMBI inhibits inflammation through the activation of autophagy in experimental spinal cord injury. International journal of molecular medicine, 39(2), 423-429.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant BAMBI protein, His Tag (CAT#: V2LY-0526-LY2296)

Mouse Recombinant BAMBI protein, hFc Tag (CAT#: V2LY-0526-LY7857)

Mouse Recombinant BAMBI protein, His Tag (CAT#: V2LY-0526-LY7858)

Related Products

Mouse Anti-BAMBI Recombinant Antibody (CBYY-0181) (CAT#: CBMAB-0182-YY)

Mouse Anti-BAMBI Recombinant Antibody (CBYY-0182) (CAT#: CBMAB-0183-YY)

Human Recombinant BAMBI protein, His Tag (CAT#: V2LY-0526-LY2296)

Mouse Anti-BAMBI Recombinant Antibody (CBYY-1680) (CAT#: CBMAB-2029-YY)

Mouse Anti-BAMBI Recombinant Antibody (CBYY-0185) (CAT#: CBMAB-0186-YY)

Mouse Anti-BAMBI Recombinant Antibody (CBYY-0180) (CAT#: CBMAB-0181-YY)

Mouse Recombinant BAMBI protein, His Tag (CAT#: V2LY-0526-LY7858)

Mouse Recombinant BAMBI protein, hFc Tag (CAT#: V2LY-0526-LY7857)

Mouse Anti-BAMBI Recombinant Antibody (3C1-1D1) (CAT#: CBMAB-A0706-LY)

Mouse Anti-BAMBI Recombinant Antibody (CBYY-2032) (CAT#: CBMAB-2381-YY)

Isotype control

For research use only. Not intended for any clinical use.

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