CADM3

The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene. [provided by RefSeq, Oct 2016]

Full Name

Cell Adhesion Molecule 3

Function

Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions (By similarity).

Biological Process

Adherens junction organization Source: Reactome
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Source: HGNC-UCL
Homophilic cell adhesion via plasma membrane adhesion molecules Source: HGNC-UCL

Cellular Location

Cell membrane; Cell junction

Topology

Extracellular: 25-330 aa
Helical: 331-351 aa
Cytoplasmic: 352-398 aa

Anti-CADM3 antibodies

Rabbit Anti-CADM3 Recombinant Antibody (CBFYC-0727) (CBMAB-C0782-FY)

Datasheet

SDS

Target: CADM3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBFYC-0727

Application*: E

Mouse Anti-CADM3 Recombinant Antibody (CBYY-I0724) (CBMAB-I1616-YY)

Datasheet

SDS

Target: CADM3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I0724

Application*: WB, IH

Rabbit Anti-CADM3 Recombinant Antibody (024) (CBMAB-C1684-LY)

Datasheet

SDS

Target: CADM3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: 024

Application*: E

Rabbit Anti-CADM3 Recombinant Antibody (3) (CBMAB-C5424-LY)

Datasheet

SDS

Target: CADM3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 3

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)