CADM3

The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene. [provided by RefSeq, Oct 2016]
Full Name
Cell Adhesion Molecule 3
Function
Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions (By similarity).
Biological Process
Adherens junction organization Source: Reactome
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Source: HGNC-UCL
Homophilic cell adhesion via plasma membrane adhesion molecules Source: HGNC-UCL
Cellular Location
Cell membrane; Cell junction
Topology
Extracellular: 25-330 aa
Helical: 331-351 aa
Cytoplasmic: 352-398 aa
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Anti-CADM3 antibodies

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Rabbit Anti-CADM3 Recombinant Antibody (3) (CBMAB-C5424-LY)

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Target: CADM3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 3
Application*: E
Datasheet SDS

Rabbit Anti-CADM3 Recombinant Antibody (024) (CBMAB-C1684-LY)

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Target: CADM3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 024
Application*: E
Datasheet SDS

Rabbit Anti-CADM3 Recombinant Antibody (CBFYC-0727) (CBMAB-C0782-FY)

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Target: CADM3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-0727
Application*: E
Datasheet SDS

Mouse Anti-CADM3 Recombinant Antibody (CBYY-I0724) (CBMAB-I1616-YY)

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Target: CADM3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0724
Application*: WB, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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