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Rabbit Anti-CADM3 Recombinant Antibody (CBFYC-0727) (CBMAB-C0782-FY)

This product is rabbit antibody that recognizes CADM3. The antibody CBFYC-0727 can be used for immunoassay techniques such as: ELISA.
See all CADM3 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse
Clone
CBFYC-0727
Antibody Isotype
IgG
Application
E

Basic Information

Immunogen
Recombinant Mouse CADM3 / NECL1 / IGSF4B Protein.
Host Species
Rabbit
Specificity
Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
ELISA1:5,000-1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-328

Target

Full Name
Cell Adhesion Molecule 3
Introduction
The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene.
Entrez Gene ID
94332
UniProt ID
Q99N28
Alternative Names
BIgR; Necl1; Tsll1; Igsf4b; Necl-1; SynCAM3
Function
Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions (By similarity).
Biological Process
Adherens junction organization Source: Reactome
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Source: HGNC-UCL
Homophilic cell adhesion via plasma membrane adhesion molecules Source: HGNC-UCL
Cellular Location
Cell membrane; Cell junction
Topology
Extracellular: 25-330 aa
Helical: 331-351 aa
Cytoplasmic: 352-398 aa
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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