CCL7

CCL7 (C-C Motif Chemokine Ligand 7) is a Protein Coding gene. Diseases associated with CCL7 include Diffuse Gastric Cancer and Status Asthmaticus. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include heparin binding and CCR1 chemokine receptor binding. An important paralog of this gene is CCL2.
Full Name
C-C Motif Chemokine Ligand 7
Function
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
Biological Process
Cell-cell signaling Source: ProtInc
Cellular calcium ion homeostasis Source: ProtInc
Cellular response to ethanol Source: Ensembl
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
Cytoskeleton organization Source: UniProtKB
Eosinophil chemotaxis Source: UniProtKB
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of cell migration Source: UniProtKB
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Positive regulation of natural killer cell chemotaxis Source: UniProtKB
Regulation of cell shape Source: UniProtKB
Response to gamma radiation Source: Ensembl
Signal transduction Source: ProtInc
Cellular Location
Secreted
PTM
O-glycosylated.
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Anti-CCL7 antibodies

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Rabbit Anti-CCL7 Recombinant Antibody (CBFYM-0954) (CBMAB-M1103-FY)

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Target: CCL7
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-0954
Application*: E
Datasheet SDS

Mouse Anti-CCL7 Recombinant Antibody (CBFYM-0951) (CBMAB-M1100-FY)

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Target: CCL7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0951
Application*: N, WB
Functional Assay
Datasheet SDS

Mouse Anti-CCL7 Recombinant Antibody (CBFYM-0950) (CBMAB-M1099-FY)

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Target: CCL7
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-0950
Application*: E, WB
Datasheet SDS

Mouse Anti-CCL7 Recombinant Antibody (CBFYM-0949) (CBMAB-M1098-FY)

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Target: CCL7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0949
Application*: E, WB, N
Functional Assay
Datasheet SDS

Mouse Anti-CCL7 Recombinant Antibody (CBFYM-0948) (CBMAB-M1097-FY)

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Target: CCL7
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-0948
Application*: E, F
Datasheet SDS

Mouse Anti-CCL7 Recombinant Antibody (CBFYM-0947) (CBMAB-M1096-FY)

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Target: CCL7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0947
Application*: E, F, IF
Datasheet SDS

Mouse Anti-CCL7 Recombinant Antibody (CBFYM-0946) (CBMAB-M1095-FY)

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Target: CCL7
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-0946
Application*: E, WB
Datasheet SDS

Mouse Anti-CCL7 Recombinant Antibody (CBFYM-0071) (CBMAB-M0080-FY)

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Target: CCL7
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0071
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CCL7 Recombinant Antibody (1015) (CBMAB-C2032-LY)

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Target: CCL7
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1015
Application*: E, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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