CDX1

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. [provided by RefSeq, Jul 2008]
Full Name
Caudal Type Homeobox 1
Function
Plays a role in transcriptional regulation (PubMed:24623306).
Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306).
Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536).
Biological Process
Animal organ morphogenesis Source: GO_Central
Anterior/posterior axis specification Source: GO_Central
Bone morphogenesis Source: Ensembl
Cell differentiation Source: GO_Central
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of somitogenesis Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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Anti-CDX1 antibodies

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Mouse Anti-CDX1 Recombinant Antibody (1E9) (CBMAB-C3993-LY)

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Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E9
Application*: E, WB
Datasheet SDS

Mouse Anti-CDX1 Recombinant Antibody (3A3) (CBMAB-1349-CN)

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Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: 3A3
Application*: IF, E
Datasheet SDS

Mouse Anti-CDX1 Recombinant Antibody (2D8) (CBMAB-1348-CN)

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Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: 2D8
Application*: WB, IF, E
Datasheet SDS

Mouse Anti-CDX1 Recombinant Antibody (1F12) (CBMAB-1347-CN)

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Target: CDX1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse
Clone: 1F12
Application*: WB, IF, E
Datasheet SDS

Rabbit Anti-CDX1 Recombinant Antibody (
11E10) (V2LY-0725-LY1578)

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Target: CDX1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 11E10
Application*: E, WB, IF
Datasheet SDS

Mouse Anti-CDX1 Recombinant Antibody (CBT3287) (V2LY-0625-LY2832)

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Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT3287
Application*: WB
Datasheet SDS

Rabbit Anti-CDX1 Recombinant Antibody (CBXC-1549) (CBMAB-C5070-CQ)

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Target: CDX1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-1549
Application*: IF, WB
Datasheet SDS

Rabbit Anti-CDX1 Recombinant Antibody (CBXC-2478) (CBMAB-C5069-CQ)

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Target: CDX1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-2478
Application*: WB
Datasheet SDS

Mouse Anti-CDX1 Recombinant Antibody (CBXC-2380) (CBMAB-C0014-CQ)

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Target: CDX1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse
Clone: CBXC-2380
Application*: WB, IF, E
Datasheet SDS

Mouse Anti-CDX1 Recombinant Antibody (CBFYC-1660) (CBMAB-C1722-FY)

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Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: CBFYC-1660
Application*: IF, E
Datasheet SDS

Mouse Anti-CDX1 Recombinant Antibody (CBFYC-1659) (CBMAB-C1721-FY)

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Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-1659
Application*: WB, IF, E, IP
Datasheet SDS

Mouse Anti-CDX1 Recombinant Antibody (CBFYC-0244) (CBMAB-C0273-FY)

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Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-0244
Application*: IF, P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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