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CDX1

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. [provided by RefSeq, Jul 2008]
Full Name
Caudal Type Homeobox 1
Function
Plays a role in transcriptional regulation (PubMed:24623306).
Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306).
Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536).
Biological Process
Animal organ morphogenesis Source: GO_Central
Anterior/posterior axis specification Source: GO_Central
Bone morphogenesis Source: Ensembl
Cell differentiation Source: GO_Central
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of somitogenesis Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus

Anti-CDX1 antibodies

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Mouse Anti-CDX1 Recombinant Antibody (CBXC-1549) (CBMAB-C5070-CQ)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-1549
Application*: E

Mouse Anti-CDX1 Recombinant Antibody (CBXC-2478) (CBMAB-C5069-CQ)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-2478
Application*: WB, E

Mouse Anti-CDX1 Recombinant Antibody (CBXC-2380) (CBMAB-C0014-CQ)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2380
Application*: WB, CI, IF

Mouse Anti-CDX1 (AA 126-215) Recombinant Antibody (CBFYC-1660) (CBMAB-C1722-FY)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYC-1660
Application*: E, IF, WB

Mouse Anti-CDX1 (AA 1-139) Recombinant Antibody (CBFYC-1659) (CBMAB-C1721-FY)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-1659
Application*: E, WB

Mouse Anti-CDX1 (N-terminus) Recombinant Antibody (CBFYC-0244) (CBMAB-C0273-FY)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0244
Application*: WB

Mouse Anti-CDX1 Recombinant Antibody (2E2) (CBMAB-C4977-LY)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E2
Application*: E

Mouse Anti-CDX1 Recombinant Antibody (1E9) (CBMAB-C3993-LY)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E9
Application*: E, WB

Mouse Anti-CDX1 Recombinant Antibody (3A3) (CBMAB-1349-CN)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3A3
Application*: IF, E

Mouse Anti-CDX1 Recombinant Antibody (2D8) (CBMAB-1348-CN)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2D8
Application*: WB, IF, E

Mouse Anti-CDX1 Recombinant Antibody (1F12) (CBMAB-1347-CN)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1F12
Application*: WB, IF, E

Mouse Anti-CDX1 Recombinant Antibody (123a) (CBMAB-AP1420LY)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 123a
Application*: ChIP, IF, WB

Mouse Anti-CDX1 Recombinant Antibody (CBLC142-LY) (CBMAB-C10855-LY)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLC142-LY
Application*: SE, IF, E, WB

Mouse Anti-CDX1 Recombinant Antibody (937CT11.6.2) (CBMAB-C2153-YY)

Datasheet SDS
Target: CDX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 937CT11.6.2
Application*: WB, E
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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