CETN1
The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. [provided by RefSeq, Jan 2015]
Full Name
Centrin 1
Function
Plays a fundamental role in microtubule-organizing center structure and function (PubMed:8175926).
Plays a role in sperm cilia formation (By similarity).
Plays a role in sperm cilia formation (By similarity).
Biological Process
Aggrephagy Source: Reactome
Cell division Source: UniProtKB-KW
Centriole replication Source: GO_Central
Mitotic cell cycle Source: GO_Central
Nucleotide-excision repair Source: GO_Central
Cell division Source: UniProtKB-KW
Centriole replication Source: GO_Central
Mitotic cell cycle Source: GO_Central
Nucleotide-excision repair Source: GO_Central
Cellular Location
Centrosome; Cilium. Centrosome of interphase and mitotic cells. In the retinal photoreceptor cells, localizes at the connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment (By similarity).
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Anti-CETN1 antibodies
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Target: CETN1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBYY-C1894
Application*: WB
Target: CETN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBFYC-1738
Application*: WB
Target: CETN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1737
Application*: WB
Target: CETN1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-1736
Application*: E
Target: CETN1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4C12
Application*: E, WB, IH
Target: CETN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2A6
Application*: E, WB, IP
Target: CETN1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1E1
Application*: IH, WB
Target: CETN1
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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