CHKA
The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.
Full Name
CHKA
Function
Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.
Biological Process
Choline metabolic process Source: Ensembl
Ethanolamine metabolic process Source: Ensembl
Lipid metabolic process Source: ProtInc
Lipid transport Source: ProtInc
Phosphatidylcholine biosynthetic process Source: UniProtKB
Phosphatidylethanolamine biosynthetic process Source: UniProtKB
Response to 3-methylcholanthrene Source: Ensembl
Response to toxic substance Source: Ensembl
Ethanolamine metabolic process Source: Ensembl
Lipid metabolic process Source: ProtInc
Lipid transport Source: ProtInc
Phosphatidylcholine biosynthetic process Source: UniProtKB
Phosphatidylethanolamine biosynthetic process Source: UniProtKB
Response to 3-methylcholanthrene Source: Ensembl
Response to toxic substance Source: Ensembl
Cellular Location
Cytoplasm
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Anti-CHKA antibodies
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Target: CHKA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: 1063
Application*: WB, IP, IF, E
Target: CHKA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBWJC-2686
Application*: WB, IP, IF, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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