CKB
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]
Full Name
Creatine Kinase B
Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Biological Process
Cellular chloride ion homeostasis Source: Ensembl
Cerebellum development Source: Ensembl
Creatine metabolic process Source: Reactome
Phosphocreatine biosynthetic process Source: GO_Central
Substantia nigra development Source: UniProtKB
Cerebellum development Source: Ensembl
Creatine metabolic process Source: Reactome
Phosphocreatine biosynthetic process Source: GO_Central
Substantia nigra development Source: UniProtKB
Cellular Location
Cytoplasm
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Anti-CKB antibodies
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Target: CKB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBXC-3075
Application*: E
Target: CKB
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXC-2842
Application*: WB, P
Target: CKB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBYY-C2846
Application*: WB
Target: CKB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-C2845
Application*: WB, F, IF, E
Target: CKB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYY-C0667
Application*: WB, P
Target: CKB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBFYC-1886
Application*: IF, WB
Target: CKB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBFYC-1885
Application*: WB, P
Target: CKB
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBFYC-1884
Application*: WB, IH, IF, E
Target: CKB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1882
Application*: E
Target: CKB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-1881
Application*: WB, IP, IF, E
Target: CKB
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-0273
Application*: WB, IP, IF, E
Target: CKB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 8E4
Application*: WB, IF, F
Target: CKB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3D5-3D11
Application*: E, IF, WB
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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