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CKMT2

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
Creatine Kinase, Mitochondrial 2
Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Biological Process
Creatine metabolic process Source: Reactome
Muscle contraction Source: ProtInc
Phosphocreatine biosynthetic process Source: GO_Central
Cellular Location
Mitochondrion inner membrane
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Anti-CKMT2 antibodies

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Mouse Anti-CKMT2 Recombinant Antibody (EG712) (CBMAB-EN866-LY)

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Target: CKMT2
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human, Mouse, Rat
Clone: EG712
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-CKMT2 Recombinant Antibody (CAP513) (CBMAB-AP1527LY)

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Target: CKMT2
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human, Mouse, Rat
Clone: CAP513
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-CKMT2 Recombinant Antibody (CAP512) (CBMAB-AP1526LY)

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Target: CKMT2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CAP512
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-CKMT2 Recombinant Antibody (CAP511) (CBMAB-AP1525LY)

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Target: CKMT2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CAP511
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CKMT2 Recombinant Antibody (CB447A) (CBMAB-CA447LY)

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Target: CKMT2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CB447A
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CKMT2 Recombinant Antibody (C6052) (CBMAB-C6052-LY)

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Target: CKMT2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: C6052
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CKMT2 Recombinant Antibody (C2944) (CBMAB-C2944-LY)

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Target: CKMT2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Rat
Clone: C2944
Application*: WB
Datasheet SDS

Mouse Anti-CKMT2 Recombinant Antibody (15B132) (CBMAB-C0379-LY)

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Target: CKMT2
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: 15B132
Application*: WB
Datasheet SDS

Mouse Anti-CKMT2 Recombinant Antibody (CBT1146) (V2LY-0625-LY2995)

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Target: CKMT2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Dog, Pig, Rabbit
Clone: CBT1146
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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