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Mouse Anti-CKMT2 Recombinant Antibody (13k35) (CBMAB-C2944-LY)

This product is antibody recognizes CKMT2. The antibody 13k35 immunoassay techniques such as: WB.
See all CKMT2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
13k35
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Purified recombinant human CKMT2 protein fragments expressed in E. coli
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Creatine Kinase, Mitochondrial 2
Introduction
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Entrez Gene ID
1160
UniProt ID
P17540
Alternative Names
Creatine Kinase, Mitochondrial 2; Creatine Kinase, Mitochondrial 2 (Sarcomeric); Basic-Type Mitochondrial Creatine Kinase; Sarcomeric Mitochondrial Creatine Kinase; EC 2.7.3.2; Mib-CK;
Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Biological Process
Creatine metabolic process Source: Reactome
Muscle contraction Source: ProtInc
Phosphocreatine biosynthetic process Source: GO_Central
Cellular Location
Mitochondrion inner membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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