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Cnp

CNP (2',3'-Cyclic Nucleotide 3' Phosphodiesterase) is a Protein Coding gene. Diseases associated with CNP include Isolated Optic Neuritis and Multiple Sclerosis. Among its related pathways are Glial Cell Differentiation and MECP2 and Associated Rett Syndrome. Gene Ontology (GO) annotations related to this gene include RNA binding and cyclic nucleotide binding.
Full Name
2',3'-Cyclic Nucleotide 3' Phosphodiesterase
Function
May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
Biological Process
Adult locomotory behavior Source: Ensembl
Aging Source: Ensembl
Axonogenesis Source: Ensembl
Chemical synaptic transmission Source: ProtInc
Cyclic nucleotide catabolic process Source: InterPro
Forebrain development Source: Ensembl
Microtubule cytoskeleton organization Source: Ensembl
Oligodendrocyte differentiation Source: Ensembl
Regulation of mitochondrial membrane permeability Source: Ensembl
Response to lipopolysaccharide Source: Ensembl
Response to toxic substance Source: Ensembl
Substantia nigra development Source: UniProtKB
Cellular Location
Membrane; Melanosome. Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Anti-Cnp antibodies

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Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Dog
Clone: mAb44289
Application*: F, P, IP, WB
Target: CNP
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EPR13005
Application*: WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Dog, Monkey
Clone: 11-5B
Application*: DB, E, F, IC, IF, C, P, WB
Target: CNP
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBWJC-2876
Application*: WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBWJC-2875
Application*: WB
Target: CNP
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBWJC-2048
Application*: WB, IP, IF
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBXC-2540
Application*: WB, IH
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2403
Application*: F
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0492
Application*: IC, IH, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2358
Application*: IF, P, WB
Target: CNP
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: CBFYC-2005
Application*: IC, IF, IH, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBFYC-2004
Application*: WB, IH, P
Target: CNP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBFYC-2003
Application*: WB, IH
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2002
Application*: F
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Rat, Human
Clone: CBFYC-0214
Application*: WB, P
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Rat, Human, Monkey
Clone: SPM238
Application*: P
Target: CNP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBCNC-230
Application*: WB, P, IF
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13A169
Application*: FC
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNC-037
Application*: E, ICC, IH, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat, Mouse
Clone: 335C6
Application*: ICC, IH
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog, Human, Mouse, Rat
Clone: CBYY-C2997
Application*: F, C, P, IP, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYY-C2982
Application*: WB, IF
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Mouse, Rat
Clone: 44289
Application*: F, C, P, IP, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 3H5
Application*: WB, IC/IF
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle, Dog, Mouse, Pig, Rabbit, Rat, Sheep
Clone: 2Q33
Application*: IC, C, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E8
Application*: E, IF, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: 2887
Application*: WB, IH, P
Target: CNP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: 2871
Application*: WB, IH
Target: CNP
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 16638
Application*: IC, IF, C, WB
Target: CNP
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: 347625
Application*: WB, IH
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 1H10
Application*: WB, IC/IF
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Hamster, Mouse
Application*: IF, IH, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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