Cnp
CNP (2',3'-Cyclic Nucleotide 3' Phosphodiesterase) is a Protein Coding gene. Diseases associated with CNP include Isolated Optic Neuritis and Multiple Sclerosis. Among its related pathways are Glial Cell Differentiation and MECP2 and Associated Rett Syndrome. Gene Ontology (GO) annotations related to this gene include RNA binding and cyclic nucleotide binding.
Full Name
2',3'-Cyclic Nucleotide 3' Phosphodiesterase
Function
May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
Biological Process
Adult locomotory behavior Source: Ensembl
Aging Source: Ensembl
Axonogenesis Source: Ensembl
Chemical synaptic transmission Source: ProtInc
Cyclic nucleotide catabolic process Source: InterPro
Forebrain development Source: Ensembl
Microtubule cytoskeleton organization Source: Ensembl
Oligodendrocyte differentiation Source: Ensembl
Regulation of mitochondrial membrane permeability Source: Ensembl
Response to lipopolysaccharide Source: Ensembl
Response to toxic substance Source: Ensembl
Substantia nigra development Source: UniProtKB
Aging Source: Ensembl
Axonogenesis Source: Ensembl
Chemical synaptic transmission Source: ProtInc
Cyclic nucleotide catabolic process Source: InterPro
Forebrain development Source: Ensembl
Microtubule cytoskeleton organization Source: Ensembl
Oligodendrocyte differentiation Source: Ensembl
Regulation of mitochondrial membrane permeability Source: Ensembl
Response to lipopolysaccharide Source: Ensembl
Response to toxic substance Source: Ensembl
Substantia nigra development Source: UniProtKB
Cellular Location
Membrane; Melanosome. Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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Anti-Cnp antibodies
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CompareTarget: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Pig
Clone: CBXC-2403
Application*: IH, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBXC-0492
Application*: IC, IH, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBXC-2358
Application*: IH, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBFYC-2005
Application*: WB, F, IH
Target: CNP
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYC-2004
Application*: WB, IF, P, F
Target: CNP
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-2003
Application*: WB, IP, IF, E, P
Target: CNP
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Mouse, Rat, Human
Clone: CBFYC-0214
Application*: WB, IP, IF, E
Target: CNP
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E8
Application*: E, IF, WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 1H10
Application*: WB, IC/IF, IH
Target: CNP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Rabbit, Goat, Sheep, Cattle, Cat, Dog, Pig, Monkey
Clone: 11-5B
Application*: IF, P, WB
Target: CNP
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBWJC-2876
Application*: WB
Target: CNP
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-2002
Application*: WB, IP, IF, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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