CREG1
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq]
Full Name
cellular repressor of E1A-stimulated genes 1
Function
May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R.
Biological Process
Multicellular organism development Source: ProtInc
Neutrophil degranulation Source: Reactome
Regulation of growth Source: UniProtKB-KW
Regulation of transcription by RNA polymerase II Source: ProtInc
Neutrophil degranulation Source: Reactome
Regulation of growth Source: UniProtKB-KW
Regulation of transcription by RNA polymerase II Source: ProtInc
Cellular Location
Secreted
PTM
N-glycosylated.
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Anti-CREG1 antibodies
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CompareTarget: CREG1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXC-1939
Application*: WB, E
Target: Creg1
Sensitivity: 0.058 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: CREG1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-220
Tag: His Tag
Target: CREG1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-220
Tag: hFc Tag
Target: CREG1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-220
Tag: His Tag
Target: CREG1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-2203
Application*: P, WB
Target: CREG1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-2202
Application*: E
Target: CREG1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-0382
Application*: WB, IP, IF, E, P
Target: CREG1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1B7
Application*: E, IH, WB
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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