CRIPT

CRIPT (CXXC Repeat Containing Interactor Of PDZ3 Domain) is a Protein Coding gene. Diseases associated with CRIPT include Short Stature With Microcephaly And Distinctive Facies and Isolated Growth Hormone Deficiency, Type Ia. Gene Ontology (GO) annotations related to this gene include protein complex binding and PDZ domain binding.

Full Name

cysteine-rich PDZ-binding protein

Function

Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses.

Biological Process

Cytoplasmic microtubule organization Source: UniProtKB
Establishment of protein localization Source: UniProtKB
Protein localization to microtubule Source: UniProtKB
Regulation of postsynaptic density protein 95 clustering Source: UniProtKB

Cellular Location

Cytoplasm; Synapse; Dendritic spine. Colocalizes with DLG4 in asymmetric synapses.

Involvement in disease

Short stature with microcephaly and distinctive facies (SSMCF):
An autosomal recessive disease characterized by dwarfism, microcephaly, and distinctive facial dysmorphism involving frontal bossing, high forehead, sparse hair and eyebrows, telecanthus, mild proptosis, anteverted nares, and flat nasal bridge.

Anti-CRIPT antibodies

Mouse Anti-CRIPT Recombinant Antibody (CBCNC-356) (CBMAB-C2829-CN)

Datasheet

SDS

Target: CRIPT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBCNC-356

Application*: E, E-capture, WB

Mouse Anti-CRIPT Recombinant Antibody (CBLNC-194) (CBMAB-1440-CN)

Datasheet

SDS

Target: CRIPT

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBLNC-194

Application*: WB, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)