Mouse Anti-CRIPT Recombinant Antibody (CBLNC-194) (V2LY-1206-LY1166)

Name: Mouse Anti-CRIPT Recombinant Antibody (CBLNC-194)
SKU: V2LY-1206-LY1166
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBLNC-194

Application

WB, ELISA

Immunogen

CRIPT (aa1-101) partial recombinant protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

cysteine-rich PDZ-binding protein

Entrez Gene ID

9419

UniProt ID

Q9P021

Function

Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses.

Biological Process

Cytoplasmic microtubule organization Source: UniProtKB
Establishment of protein localization Source: UniProtKB
Protein localization to microtubule Source: UniProtKB
Regulation of postsynaptic density protein 95 clustering Source: UniProtKB

Cellular Location

Cytoplasm; Synapse; Dendritic spine. Colocalizes with DLG4 in asymmetric synapses.

Involvement in disease

Short stature with microcephaly and distinctive facies (SSMCF):
An autosomal recessive disease characterized by dwarfism, microcephaly, and distinctive facial dysmorphism involving frontal bossing, high forehead, sparse hair and eyebrows, telecanthus, mild proptosis, anteverted nares, and flat nasal bridge.

Omelchenko, A., Menon, H., Donofrio, S. G., Kumar, G., Chapman, H. M., Roshal, J., ... & Firestein, B. L. (2020). Interaction between CRIPT and PSD-95 is required for proper dendritic arborization in hippocampal neurons. Molecular neurobiology, 57(5), 2479-2493.

Zhang, L., Jablonski, A. M., Mojsilovic-Petrovic, J., Ding, H., Seeholzer, S., Newton, I. P., ... & Kalb, R. G. (2017). SAP97 binding partner CRIPT promotes dendrite growth in vitro and in vivo. Eneuro, 4(6).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Human Recombinant CRIPT protein, His Tag (CAT#: V2LY-0526-LY3375)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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