CTSS

CTSS (Cathepsin S) is a Protein Coding gene. Diseases associated with CTSS include Cercarial Dermatitis and Mandibular Cancer. Among its related pathways are Bacterial infections in CF airways and Innate Immune System. Gene Ontology (GO) annotations related to this gene include peptidase activity and cysteine-type peptidase activity. An important paralog of this gene is CTSK.
Full Name
Cathepsin S
Function
Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation (PubMed:30612035).

The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
Biological Process
Adaptive immune response Source: UniProtKB
Antigen processing and presentation Source: UniProtKB
Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: UniProtKB
Antigen processing and presentation of peptide antigen Source: CACAO
Basement membrane disassembly Source: BHF-UCL
Cellular response to thyroid hormone stimulus Source: UniProtKB
Collagen catabolic process Source: BHF-UCL
Extracellular matrix disassembly Source: Reactome
Immune response Source: GO_Central
Neutrophil degranulation Source: Reactome
Positive regulation of cation channel activity Source: CACAO
Protein processing Source: CACAO
Proteolysis Source: CAFA
Proteolysis involved in cellular protein catabolic process Source: BHF-UCL
Response to acidic pH Source: CACAO
Toll-like receptor signaling pathway Source: Reactome
Cellular Location
Secreted; Lysosome; Phagosome
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Anti-CTSS antibodies

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Rabbit Anti-CTSS Recombinant Antibody (
9B10) (V2LY-0725-LY1364)

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Target: CTSS
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 9B10
Application*: E, IH
Datasheet SDS

Rat Anti-CTSS Recombinant Antibody (CBXC-1041) (V2LY-0125-LY478)

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Target: CTSS
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-1041
Application*: WB, IP
Datasheet SDS

Rat Anti-CTSS Recombinant Antibody (CBFYC-2459) (V2LY-0125-LY477)

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Target: CTSS
Host: Rat
Antibody Isotype: IgG2
Specificity: Human
Clone: CBFYC-2459
Application*: WB
Datasheet SDS

Rabbit Anti-CTSS Recombinant Antibody (CBFYC-0401) (V2LY-0125-LY476)

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Target: CTSS
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-0401
Application*: WB, B, E, IF, IH
Datasheet SDS

Rat Anti-CTSS Recombinant Antibody (C3183) (V2LY-0125-LY475)

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Target: CTSS
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Rat
Clone: C3183
Application*: WB
Datasheet SDS

Mouse Anti-CTSS Recombinant Antibody (C0382) (V2LY-0125-LY473)

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Target: CTSS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C0382
Application*: E
Datasheet SDS

Mouse Anti-CTSS Recombinant Antibody (1494) (V2LY-0125-LY472)

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Target: CTSS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1494
Application*: E
Datasheet SDS

Mouse Anti-CTSS Recombinant Antibody (CAP1027) (CBMAB-AP1787LY)

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Target: CTSS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CAP1027
Application*: E
Datasheet SDS

Mouse Anti-CTSS Recombinant Antibody (CBCNC-493) (CBMAB-C3157-CN)

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Target: CTSS
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBCNC-493
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-CTSS Recombinant Antibody (CBCNC-492) (CBMAB-C3156-CN)

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Target: CTSS
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBCNC-492
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-CTSS Recombinant Antibody (C4664) (CBMAB-C4664WJ)

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Target: CTSS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C4664
Application*: E
Datasheet SDS

Mouse Anti-CTSS Recombinant Antibody (CBWJC-3437) (CBMAB-C4663WJ)

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Target: CTSS
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBWJC-3437
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-CTSS Recombinant Antibody (CBXC-1692) (CBMAB-C3522-CQ)

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Target: CTSS
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXC-1692
Application*: E, WB, IF
Datasheet SDS

Rabbit Anti-CTSS Recombinant Antibody (054) (CBMAB-C1790-LY)

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Target: CTSS
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 054
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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