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CXCL1

CXCL1 (C-X-C Motif Chemokine Ligand 1) is a Protein Coding gene. Diseases associated with CXCL1 include Kaposi Sarcoma and Melanoma. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include receptor binding and chemokine activity. An important paralog of this gene is CXCL2.
Full Name
C-X-C Motif Chemokine Ligand 1
Function
Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
Biological Process
Actin cytoskeleton organization Source: ProtInc
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cellular response to lipopolysaccharide Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
Cytokine-mediated signaling pathway Source: Reactome
G protein-coupled receptor signaling pathway Source: Reactome
Inflammatory response Source: GO_Central
Intracellular signal transduction Source: ProtInc
Killing of cells of other organism Source: UniProtKB
Negative regulation of cell population proliferation Source: ProtInc
Nervous system development Source: ProtInc
Neutrophil chemotaxis Source: GO_Central
Neutrophil degranulation Source: Reactome
Signal transduction Source: ProtInc
Cellular Location
Secreted
PTM
N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.

Anti-CXCL1 antibodies

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Mouse Anti-CXCL1 Recombinant Antibody (CBWJC-3474) (CBMAB-C4704WJ)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-3474
Application*: F

Rabbit Anti-CXCL1 Recombinant Antibody (CBWJC-3473) (CBMAB-C4703WJ)

Datasheet SDS
Target: CXCL1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-3473
Application*: WB

Mouse Anti-CXCL1 Recombinant Antibody (CBWJC-3472) (CBMAB-C4702WJ)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBWJC-3472
Application*: N, WB

Mouse Anti-CXCL1 Recombinant Antibody (CBXC-1096) (CBMAB-C4210-CQ)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1096
Application*: WB, N

Rat Anti-CXCL1 Recombinant Antibody (CBXC-1490) (CBMAB-C3342-CQ)

Datasheet SDS
Target: CXCL1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXC-1490
Application*: N, WB

Mouse Anti-CXCL1 Recombinant Antibody (CBXC-1068) (CBMAB-C1332-CQ)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1068
Application*: IS

Mouse Anti-CXCL1 Recombinant Antibody (CBXC-1004) (CBMAB-C1266-CQ)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-1004
Application*: IS

Mouse Anti-CXCL1 (AA 36-107) Recombinant Antibody (CBYY-C2346) (CBMAB-C3784-YY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-C2346
Application*: E, WB

Mouse Anti-CXCL1 Recombinant Antibody (CBYY-C2345) (CBMAB-C3783-YY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgM
Specificity: Rat
Clone: CBYY-C2345
Application*: WB

Rat Anti-CXCL1 Recombinant Antibody (CBYY-C0249) (CBMAB-C0723-YY)

Datasheet SDS
Target: CXCL1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-C0249
Application*: WB, N, E(Cap)

Mouse Anti-CXCL1 Recombinant Antibody (CBYY-C0009) (CBMAB-C0017-YY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0009
Application*: WB, N

Rabbit Anti-CXCL1 Recombinant Antibody (CBFYC-2490) (CBMAB-C2563-FY)

Datasheet SDS
Target: CXCL1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-2490
Application*: E

Mouse Anti-CXCL1 Recombinant Antibody (CBFYC-2488) (CBMAB-C2561-FY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: CBFYC-2488
Application*: WB, N

Mouse Anti-CXCL1 Recombinant Antibody (CBFYC-2487) (CBMAB-C2560-FY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBFYC-2487
Application*: N, WB

Mouse Anti-CXCL1 Recombinant Antibody (CBFYC-2486) (CBMAB-C2559-FY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBFYC-2486
Application*: C, P

Mouse Anti-CXCL1 Recombinant Antibody (CBFYC-0507) (CBMAB-C0558-FY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0507
Application*: F

Mouse Anti-CXCL1 Recombinant Antibody (CBFYC-0426) (CBMAB-C0471-FY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-0426
Application*: ED, E F, N, WB

Rabbit Anti-CXCL1 Recombinant Antibody (CBFYC-0218) (CBMAB-C0245-FY)

Datasheet SDS
Target: CXCL1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-0218
Application*: F

Mouse Anti-CXCL1 (AA 36-107) Recombinant Antibody (CBFYM-1059) (CBMAB-M1212-FY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-1059
Application*: E, WB

Mouse Anti-CXCL1 Recombinant Antibody (CBFYH-0117) (CBMAB-H0978-FY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0117
Application*: E, WB

Mouse Anti-CXCL1 Recombinant Antibody (9A18) (CBMAB-1502-CN)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 9A18
Application*: WB, E

Mouse Anti-CXCL1 Recombinant Antibody (A1290) (CBMAB-AP5065LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: A1290
Application*: ICC, IHC, IP, WB

Mouse Anti-CXCL1 Recombinant Antibody (A1289) (CBMAB-AP5061LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A1289
Application*: ICC, IHC, IP, WB

Mouse Anti-CXCL1 Recombinant Antibody (A1288) (CBMAB-AP5066LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Rat
Clone: A1288
Application*: ICC, IHC, IP

Mouse Anti-CXCL1 Recombinant Antibody (W3ZLCXC) (CBMAB-C11351-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: W3ZLCXC
Application*: F

Mouse Anti-CXCL1 Recombinant Antibody (CBLC-LY-018) (CBMAB-C9417-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLC-LY-018
Application*: E, WB

Mouse Anti-CXCL1 Recombinant Antibody (8k221) (CBMAB-C9286-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 8k221
Application*: E, IH, IP, WB

Mouse Anti-CXCL1 Recombinant Antibody (7A11) (CBMAB-C8549-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 7A11
Application*: E, WB

Mouse Anti-CXCL1 Recombinant Antibody (6G2) (CBMAB-C8307-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgM
Specificity: Rat
Clone: 6G2
Application*: WB

Mouse Anti-CXCL1 Recombinant Antibody (2A9) (CBMAB-C4637-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: 2A9
Application*: N, WB

Mouse Anti-CXCL1 Recombinant Antibody (1B10) (CBMAB-C3611-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 1B10
Application*: C, P

Mouse Anti-CXCL1 Recombinant Antibody (14L302) (CBMAB-C3160-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L302
Application*: N, WB

Rat Anti-CXCL1 Recombinant Antibody (13H12) (CBMAB-C2890-LY)

Datasheet SDS
Target: CXCL1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 13H12
Application*: N, WB

Mouse Anti-CXCL1 Recombinant Antibody (12) (CBMAB-C2564-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: 12
Application*: E

Rabbit Anti-CXCL1 Recombinant Antibody (012) (CBMAB-C1612-LY)

Datasheet SDS
Target: CXCL1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 012
Application*: E

Rat Anti-CXCL1 Recombinant Antibody (48415) (CBMAB-C1344-LY)

Datasheet SDS
Target: CXCL1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 48415
Application*: WB, N, EC

Mouse Anti-CXCL1 Recombinant Antibody (31716) (CBMAB-C0952-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 31716
Application*: WB, N

Mouse Anti-CXCL1 Recombinant Antibody (29702) (CBMAB-C0804-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 29702
Application*: WB, IS, MC

Mouse Anti-CXCL1 Recombinant Antibody (251021) (CBMAB-C0737-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: 251021
Application*: WB, N

Mouse Anti-CXCL1 Recombinant Antibody (20326R) (CBMAB-C0580-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 20326R
Application*: N, IS, EC

Mouse Anti-CXCL1 Recombinant Antibody (20326) (CBMAB-C0579-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 20326
Application*: WB, N, IS, MC, EC

Mouse Anti-CXCL1 Recombinant Antibody (186413) (CBMAB-C0445-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: 186413
Application*: WB, N

Rabbit Anti-CXCL1 Recombinant Antibody (1174A) (CBMAB-C0218-LY)

Datasheet SDS
Target: CXCL1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 1174A
Application*: IS

Mouse Anti-CXCL1 Recombinant Antibody (CBWJN-1169) (CBMAB-N1150-WJ)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJN-1169
Application*: WB, IC, P, E

Mouse Anti-CXCL1 Recombinant Antibody (CBLG1-380) (CBMAB-G1495-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-380
Application*: E, WB

Rat Anti-CXCL1 Recombinant Antibody (RM0201-13H12) (CBMAB-G1494-LY)

Datasheet SDS
Target: CXCL1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: RM0201-13H12
Application*: WB

Mouse Anti-CXCL1 Recombinant Antibody (MM0208-9A18) (CBMAB-G1493-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: MM0208-9A18
Application*: WB

Mouse Anti-CXCL1 Recombinant Antibody (CBLG1-3132) (CBMAB-G1492-LY)

Datasheet SDS
Target: CXCL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-3132
Application*: WB

CXCL1 Matched Antibody Pair (321) (APMAB-321LY)

Datasheet SDS
Target: CXCL1
Specificity: Human

CXCL1 Matched Antibody Pair (320) (APMAB-320LY)

Datasheet SDS
Target: CXCL1
Specificity: Human
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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