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CXCL1 Matched Antibody Pair (321) (APMAB-321LY)

This antibody pair set can be used for detecting and quantifying protein level of human CXCL1.
See all CXCL1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-CXCL1 polyclonal antibody, 100 ug
Detection Antibody
Anti-CXCL1 Mouse monoclonal, IgG2a antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
CXCL1 (C-X-C Motif Chemokine Ligand 1) is a Protein Coding gene. Diseases associated with CXCL1 include Kaposi Sarcoma and Melanoma. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include receptor binding and chemokine activity. An important paralog of this gene is CXCL2.
Alternative Names
C-X-C Motif Chemokine Ligand 1; Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha); GRO1 Oncogene (Melanoma Growth Stimulating Activity, Alpha); Melanoma Growth Stimulating Activity, Alpha; Neutrophil-Activating Protein 3; Fibroblast Secretory Protein; C-X-C Motif Chemokine 1; GRO-Alpha(1-73); NAP-3; SCYB1; GROa;
Entrez Gene ID
2919
UniProt ID
P09341

Jiang, Y., Xi, Y., Li, Y., Zuo, Z., Zeng, C., Fan, J., ... & Guo, Y. (2022). Ethanol promoting the upregulation of CXC Motif Chemokine Ligand 1（ CXCL1） and CXC Motif Chemokine Ligand 6（ CXCL6） in models of early alcoholic liver disease. Bioengineered, 13(3), 4688-4701.

Zeng, X., Dong, X., Ma, Y., & Yao, J. (2022). Chemokine (CXC motif) ligand 1 maintains the immune surveillance function of natural killer cells via the PDK2/mTOR signaling pathway. Cell Biology and Toxicology, 1-15.

Ciummo, S. L., D’Antonio, L., Sorrentino, C., Fieni, C., Lanuti, P., Stassi, G., ... & Di Carlo, E. (2021). The CXC motif chemokine ligand 1 sustains breast cancer stem cell self-renewal and promotes tumor progression and immune escape programs. Frontiers in Cell and Developmental Biology, 9, 1479.

Gong, Y. Z., Ma, H., Ruan, G. T., Zhu, L. C., Liao, X. W., Wang, S., ... & Gao, F. (2021). Diagnosis and prognostic value of CXC motif chemokine ligand 1 in colon adenocarcinoma based on The Cancer Genome Atlas and Guangxi cohort. Journal of Cancer, 12(18), 5506.

Wang, S., Wang, N., Huang, X., Yang, B., Zheng, Y., Zhang, J., ... & Wang, Z. (2020). Baohuoside i suppresses breast cancer metastasis by downregulating the tumor-associated macrophages/CXC motif chemokine ligand 1 pathway. Phytomedicine, 78, 153331.

Wang, S., Liu, X., Huang, R., Zheng, Y., Wang, N., Yang, B., ... & Wang, Z. (2019). XIAOPI formula inhibits breast Cancer stem cells via suppressing tumor-associated macrophages/CXC motif chemokine ligand 1 pathway. Frontiers in pharmacology, 1371.

Hatano, T., Yashiro, M., Fujikawa, H., & Motomura, H. (2018). CXC Motif Ligand 1 (CXCL1) from melanoma cells down-regulates the invasion of their metastatic melanoma cells. Oncotarget, 9(57), 31090.

Zhuo, C., Wu, X., Li, J., Hu, D., Jian, J., Chen, C., ... & Yang, C. (2018). Chemokine (CXC motif) ligand 1 is associated with tumor progression and poor prognosis in patients with colorectal cancer. Bioscience reports, 38(4).

Amin, M., Vakilian, A., Mahmoodi, M. H., Hassanshahi, G., Falahati-Pour, S. K., Dolatabadi, M. R., & Nadimi, A. E. (2017). Circulatory levels of CXC motif chemokine ligands 1, 9, and 10 are elevated in patients with ischemic stroke. The Eurasian journal of medicine, 49(2), 92.

Deftu, A. F., Filippi, A., Shibsaki, K., Gheorghe, R. O., Chiritoiu, M., & Ristoiu, V. (2017). Chemokine (CXC motif) ligand 1 (CXCL1) and chemokine (CXC motif) ligand 2 (CXCL2) modulate the activity of TRPV1+/IB4+ cultured rat dorsal root ganglia neurons upon short-term and acute application. Journal of Physiology and Pharmacology: an Official Journal of the Polish Physiological Society, 68(3), 385-395.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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