DPP3

This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized. [provided by RefSeq]
Full Name
dipeptidyl-peptidase 3
Function
Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin (PubMed:3233187, PubMed:1515063).

Also cleaves Arg-Arg-beta-naphthylamide (in vitro) (PubMed:9425109, PubMed:3233187, PubMed:11209758).
Biological Process
Proteolysis Source: UniProtKB
Cellular Location
Cytosol
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Anti-DPP3 antibodies

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Rat Anti-DPP3 Recombinant Antibody (1E7) (CBMAB-D1567-YC)

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Target: DPP3
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1E7
Application*: IF, IH, WB
Datasheet SDS

Rabbit Anti-DPP3 Recombinant Antibody (1C11) (CBMAB-D1566-YC)

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Target: DPP3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 1C11
Application*: F, WB, P
Datasheet SDS

Mouse Anti-DPP3 Recombinant Antibody (3C6) (V2LY-0425-LY837)

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Target: DPP3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 3C6
Application*: WB, E
Datasheet SDS

Rat Anti-DPP3 Recombinant Antibody (D1571) (V2LY-0425-LY836)

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Target: DPP3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: D1571
Application*: N, WB
Datasheet SDS

Mouse Anti-DPP3 Recombinant Antibody (D1569) (V2LY-0425-LY835)

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Target: DPP3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: D1569
Application*: IF, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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