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DPP3

This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized. [provided by RefSeq]

Full Name

dipeptidyl-peptidase 3

Function

Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin (PubMed:3233187, PubMed:1515063).

Also cleaves Arg-Arg-beta-naphthylamide (in vitro) (PubMed:9425109, PubMed:3233187, PubMed:11209758).

Biological Process

Proteolysis Source: UniProtKB

Cellular Location

Cytosol

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Anti-DPP3 antibodies

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Rat Anti-DPP3 Recombinant Antibody (1E7) (CBMAB-D1567-YC)

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Target: DPP3

Host: Rat

Antibody Isotype: IgG2b

Specificity: Human

Clone: 1E7

Application*: IF, IH, WB

Rabbit Anti-DPP3 Recombinant Antibody (1C11) (CBMAB-D1566-YC)

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Target: DPP3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 1C11

Application*: F, WB, P

Mouse Anti-DPP3 Recombinant Antibody (3C6) (V2LY-0425-LY837)

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Target: DPP3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: 3C6

Application*: WB, E

Rat Anti-DPP3 Recombinant Antibody (D1571) (V2LY-0425-LY836)

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Target: DPP3

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: D1571

Application*: N, WB

Mouse Anti-DPP3 Recombinant Antibody (D1569) (V2LY-0425-LY835)

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Target: DPP3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: D1569

Application*: IF, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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