DYNC1I1

DYNC1I1 (Dynein Cytoplasmic 1 Intermediate Chain 1) is a Protein Coding gene. Diseases associated with DYNC1I1 include Paranoid Personality Disorder and Split-Hand/Foot Malformation 2. Among its related pathways are COPI-independent Golgi-to-ER retrograde traffic and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include microtubule binding and motor activity. An important paralog of this gene is DYNC1I2.
Full Name
dynein cytoplasmic 1 intermediate chain 1
Research Area
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Biological Process
Microtubule-based movement Source: GO_Central
Transport along microtubule Source: GO_Central
Vesicle transport along microtubule Source: UniProtKB
Cellular Location
Cytoplasm; Spindle pole; Kinetochore
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Anti-DYNC1I1 antibodies

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Mouse Anti-DYNC1I1 Recombinant Antibody (CBYCD-110) (V2LY-0425-LY1135)

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Target: DYNC1I1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: CBYCD-110
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-DYNC1I1 Recombinant Antibody (1091) (V2LY-0425-LY1134)

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Target: DYNC1I1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Zebrafish, Rat, Common fruit fly
Clone: 1091
Application*: WB, IP, IF, F, IH
Datasheet SDS

Mouse Anti-DYNC1I1 Recombinant Antibody (CBYCD-110) (CBMAB-D1990-YC)

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Target: DYNC1I1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Cattle
Clone: CBYCD-110
Application*: C, WB
Datasheet SDS

Mouse Anti-DYNC1I1 Monoclonal Antibody (70-1) (CBMAB-1091-YC)

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Target: DYNC1I1
Host: Mouse
Antibody Isotype: IgM
Specificity: Human, Chicken, Zebrafish, Rat
Clone: 70-1
Application*: E, IC, IF, IP, DB, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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