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Mouse Anti-DYNC1I1 Monoclonal Antibody (70-1) (CBMAB-1091-YC)

Provided herein is a mouse monoclonal antibody against Human DYNC1I1. The antibody, clone 70-1, can be used for immunoassay techniques, such as ELISA, ICC, IF, IP, Dot and WB.
See all DYNC1I1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Chicken, Zebrafish, Rat
Clone
70-1
Antibody Isotype
IgM
Application
ELISA, ICC, IF, IP, Dot, WB

Basic Information

Immunogen
Cytoplasmic full length native protein (purified from chick brain)
Specificity
Human, Chicken, Zebrafish, Rat
Antibody Isotype
IgM
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
dynein cytoplasmic 1 intermediate chain 1
Introduction
DYNC1I1 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. DYNC1I1 may play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Entrez Gene ID
Human1780
Chicken420571
Rat29564
Zebrafish561525
UniProt ID
HumanO14576
ChickenE1C7N2
RatQ63100
ZebrafishA1A5Y4
Alternative Names
DNCI1; DNCIC1
Research Area
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Biological Process
Microtubule-based movement Source: GO_Central
Transport along microtubule Source: GO_Central
Vesicle transport along microtubule Source: UniProtKB
Cellular Location
Cytoplasm; Spindle pole; Kinetochore
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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