Sign in or Register

Keywords Search | Target Search

FCAR

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Full Name

Fc Fragment Of IgA Receptor

Research Area

Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.

Biological Process

Cellular response to granulocyte macrophage colony-stimulating factor stimulus Source: CAFA
Cellular response to interferon-alpha Source: CAFA
Cellular response to interferon-gamma Source: CAFA
Cellular response to interleukin-6 Source: CAFA
Cellular response to lipopolysaccharide Source: CAFA
Cellular response to tumor necrosis factor Source: CAFA
Fc receptor signaling pathway Source: CAFA
Immune response Source: ProtInc
Neutrophil activation Source: CAFA
Neutrophil mediated immunity Source: CAFA
Positive regulation of neutrophil apoptotic process Source: CAFA
Positive regulation of oxidative stress-induced cell death Source: CAFA

Cellular Location

Isoform A.1&A.2&A.3: Cell membrane
Isoform B: Secreted
Isoform B-delta-S2: Secreted

Topology

Extracellular: 22-227
Helical: 228-246
Cytoplasmic: 247-287

Anti-FCAR antibodies

Mouse Anti-FCAR Recombinant Antibody (CBWJC-3665) (CBMAB-C4913WJ)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJC-3665

Application*: F

Mouse Anti-FCAR Recombinant Antibody (A59) (CBMAB-C2870WJ)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: A59

Application*: F, C

Human Anti-FCAR Recombinant Antibody (CBXC-0760) (CBMAB-C1874-CQ)

SDS

Target: FCAR

Host: Human

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-0760

Application*: F

Mouse Anti-FCAR Recombinant Antibody (CBYY-C2472) (CBMAB-C3912-YY)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-C2472

Application*: E, F

Rabbit Anti-FCAR Recombinant Antibody (CBYY-C2471) (CBMAB-C3911-YY)

SDS

Target: FCAR

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBYY-C2471

Application*: E

Rabbit Anti-FCAR Recombinant Antibody (CBFYC-2659) (CBMAB-C2733-FY)

SDS

Target: FCAR

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYC-2659

Application*: EC

Rabbit Anti-FCAR Recombinant Antibody (CBFYC-2658) (CBMAB-C2732-FY)

SDS

Target: FCAR

Host: Rabbit

Antibody Isotype: IgG

Specificity: Rat

Clone: CBFYC-2658

Application*: E

Mouse Anti-FCAR Recombinant Antibody (CBFYC-2657) (CBMAB-C2731-FY)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYC-2657

Application*: WB

Mouse Anti-FCAR Recombinant Antibody (CBFYC-2656) (CBMAB-C2730-FY)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-2656

Application*: F, IF

Mouse Anti-FCAR Recombinant Antibody (CBFYC-0417) (CBMAB-C0461-FY)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-0417

Application*: F

Mouse Anti-FCAR Recombinant Antibody (6G3G3E7) (CBMAB-C8313-LY)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6G3G3E7

Application*: E, F

Rabbit Anti-FCAR Recombinant Antibody (6) (CBMAB-C7846-LY)

SDS

Target: FCAR

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 6

Application*: E

Mouse Anti-FCAR Recombinant Antibody (10K142) (CBMAB-C2373-LY)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 10K142

Application*: WB

Mouse Anti-FCAR Recombinant Antibody (10K141) (CBMAB-C2372-LY)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 10K141

Application*: F, IF

Mouse Anti-FCAR Recombinant Antibody (10K140) (CBMAB-C2371-LY)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 10K140

Application*: F

Rabbit Anti-FCAR Recombinant Antibody (013) (CBMAB-C1619-LY)

SDS

Target: FCAR

Host: Rabbit

Antibody Isotype: IgG

Specificity: Rat

Clone: 013

Application*: E

Rabbit Anti-FCAR Recombinant Antibody (002) (CBMAB-C1485-LY)

SDS

Target: FCAR

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 002

Application*: EC

Mouse Anti-FCAR Recombinant Antibody (3H1742) (CBMAB-C1199-LY)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 3H1742

Application*: E, F, IP, WB

Mouse Anti-FCAR Recombinant Antibody (MIP68b) (CBMAB-F2578-CQ)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: MIP68b

Application*: WB

Mouse Anti-FCAR Recombinant Antibody (CBXF-0436) (CBMAB-F2257-CQ)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-0436

Application*: WB

Mouse Anti-FCAR Recombinant Antibody (CBXF-0435) (CBMAB-F2256-CQ)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-0435

Application*: F, I

Mouse Anti-FCAR Recombinant Antibody (CBXF-0434) (CBMAB-F2255-CQ)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-0434

Application*: F, IF, I

Mouse Anti-FCAR Recombinant Antibody (CBXF-0433) (CBMAB-F2254-CQ)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-0433

Application*: F, IF

Mouse Anti-FCAR Recombinant Antibody (CBXF-0429) (CBMAB-F0369-CQ)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-0429

Application*: E, F, IP, WB

Mouse Anti-FCAR Recombinant Antibody (CBXF-2579) (CBMAB-F0164-CQ)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-2579

Application*: F

Mouse Anti-FCAR Recombinant Antibody (MIP8a) (CBMAB-F0066-CQ)

SDS

Target: FCAR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: MIP8a

Application*: WB, F, E, IP

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

Go to
Compare