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Mouse Anti-FCAR Recombinant Antibody (CBT4168) (V2LY-0625-LY1072)

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Tested Data

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT4168
Antibody Isotype
IgG1
Application
FC

Basic Information

Immunogen
Purified recombinant fragment of human CD89 (AA: extra 22-227) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Entrez Gene ID
UniProt ID
Research Area
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
Biological Process
Cellular response to granulocyte macrophage colony-stimulating factor stimulus Source: CAFA
Cellular response to interferon-alpha Source: CAFA
Cellular response to interferon-gamma Source: CAFA
Cellular response to interleukin-6 Source: CAFA
Cellular response to lipopolysaccharide Source: CAFA
Cellular response to tumor necrosis factor Source: CAFA
Fc receptor signaling pathway Source: CAFA
Immune response Source: ProtInc
Neutrophil activation Source: CAFA
Neutrophil mediated immunity Source: CAFA
Positive regulation of neutrophil apoptotic process Source: CAFA
Positive regulation of oxidative stress-induced cell death Source: CAFA
Cellular Location
Isoform A.1&A.2&A.3: Cell membrane
Isoform B: Secreted
Isoform B-delta-S2: Secreted
Topology
Extracellular: 22-227
Helical: 228-246
Cytoplasmic: 247-287
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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