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FCER2

The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Full Name
Fc Fragment Of IgE Receptor II
Research Area
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Biological Process
Positive regulation of humoral immune response mediated by circulating immunoglobulin Source: Ensembl
Positive regulation of killing of cells of other organism Source: BHF-UCL
Positive regulation of nitric-oxide synthase activity Source: BHF-UCL
Positive regulation of nitric-oxide synthase biosynthetic process Source: BHF-UCL
Cellular Location
Cell membrane; Cell membrane; Secreted. Also exists as a soluble excreted form, sCD23.
Topology
Cytoplasmic: 1-21
Helical: 22-47
Extracellular: 48-321
PTM
N- and O-glycosylated.
The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.

Anti-FCER2 antibodies

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Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2651
Application*: F, FN
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0648
Application*: F, C, P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0975
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2724
Application*: WB, F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: EBVCS-5
Application*: F, IP, MC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C2480
Application*: E, WB
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYY-C2479
Application*: IF, F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: CBYY-C2478
Application*: F, IH, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C2477
Application*: F, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2476
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C2475
Application*: E, P
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-C2474
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2473
Application*: F, IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0621
Application*: F, IH, WB
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 691632
Application*: F, MC
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-C0449
Application*: F, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0386
Application*: F, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5000
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0097
Application*: F
Target: FCER2
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: CBFYC-2662
Application*: IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-2661
Application*: EC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2660
Application*: F, N, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0270
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-0021
Application*: E, P
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 7
Application*: IF/C, F
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: 5K250
Application*: F, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 2L6
Application*: WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 2F2
Application*: IH
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 12K30
Application*: F
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 011
Application*: E
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 1E9
Application*: IH
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 007
Application*: F, IC/IF, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-2918
Application*: E, IP, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBXF-0442
Application*: IP, E, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: TS1/18
Application*: P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: T1
Application*: F, IF, C
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP23
Application*: IH
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP163
Application*: F, P, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: S52
Application*: E, IP, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 9B6
Application*: WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6C2
Application*: P, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5E3
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1468
Application*: WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0457
Application*: IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-0456
Application*: P, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1B12
Application*: P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-0455
Application*: C, P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0451
Application*: F, P, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0450
Application*: F, C, P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0449
Application*: F, IH, IP, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-0443
Application*: E, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3A2
Application*: P, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3552
Application*: IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2310
Application*: F, C
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBXF-2334
Application*: E, IF, IH, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXF-2322
Application*: E, IF, IH, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3735
Application*: E, WB, P, IF, F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: Bu38
Application*: F, P, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: EBVCS2
Application*: F, IH, FN, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: LVNC-4
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: Tu1
Application*: F, C, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0452
Application*: F, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-0447
Application*: F, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-0446
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP746
Application*: IHC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF072
Application*: ELISA, WB, IHC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CB358A
Application*: ELISA, IHC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CB222A
Application*: ELISA, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CB201
Application*: WB, IHC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB200
Application*: IF, FC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB199
Application*: IF, FC
Target: FCER2
Host: Mouse
Specificity: Human
Clone: IHC023
Application*: IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MHM6
Application*: P, C
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MM0164-2C23
Application*: WB, N, F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M-L233
Application*: F
Target: FCER2
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: CBCNC-600
Application*: IH
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 5G43
Application*: E, IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2A7
Application*: E, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13H86
Application*: FC, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 0.N.92
Application*: IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H168
Application*: FC, IH, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10B1094
Application*: FC, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: KB61
Application*: F, IH, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2ZC115
Application*: IH
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: 2G8
Application*: F, E, C
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 7H45
Application*: E, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: 5K232
Application*: F, IH, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5J77
Application*: F, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5F27
Application*: F, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5B5
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5
Application*: E, P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1130
Application*: F, IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C23
Application*: F, N, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B6
Application*: WB, IH
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 176
Application*: E
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 160
Application*: P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 14L174
Application*: F, N, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 05
Application*: E, P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3H1136
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 138633
Application*: EC
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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