FCER2
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Full Name
Fc Fragment Of IgE Receptor II
Research Area
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Biological Process
Positive regulation of humoral immune response mediated by circulating immunoglobulin Source: Ensembl
Positive regulation of killing of cells of other organism Source: BHF-UCL
Positive regulation of nitric-oxide synthase activity Source: BHF-UCL
Positive regulation of nitric-oxide synthase biosynthetic process Source: BHF-UCL
Positive regulation of killing of cells of other organism Source: BHF-UCL
Positive regulation of nitric-oxide synthase activity Source: BHF-UCL
Positive regulation of nitric-oxide synthase biosynthetic process Source: BHF-UCL
Cellular Location
Cell membrane; Cell membrane; Secreted. Also exists as a soluble excreted form, sCD23.
Topology
Cytoplasmic: 1-21
Helical: 22-47
Extracellular: 48-321
Helical: 22-47
Extracellular: 48-321
PTM
N- and O-glycosylated.
The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
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Anti-FCER2 antibodies
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CompareTarget: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CB358A
Application*: ELISA, IHC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 4AEBVCS2
Application*: FC, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP749
Application*: ELISA, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CAP748
Application*: ELISA, IHC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 168
Application*: ELISA, IHC, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 608
Application*: ELISA, IHC, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: PT0033
Application*: IHC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP747
Application*: IHC, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP746
Application*: IHC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CB222A
Application*: ELISA, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CB201
Application*: WB, IHC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB200
Application*: IF, FC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB199
Application*: IF, FC
Target: FCER2
Host: Mouse
Specificity: Human
Clone: IHC023
Application*: IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MHM6
Application*: P, C
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MM0164-2C23
Application*: WB, N, F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M-L233
Application*: F
Target: FCER2
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: CBCNC-600
Application*: IH
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 5G43
Application*: E, IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2A7
Application*: E, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13H86
Application*: FC, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 0.N.92
Application*: IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H168
Application*: FC, IH, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10B1094
Application*: FC, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: LT23
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-3670
Application*: IP, IF, IH, F
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: E28-S
Application*: IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJC-3668
Application*: IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: D3.6
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-G6
Application*: F, IH
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: B3B4
Application*: F, IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2148
Application*: F, FN
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: KB61
Application*: F, IH, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2ZC115
Application*: IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1837
Application*: F, IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2651
Application*: F, FN
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0648
Application*: F, C, P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0975
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2724
Application*: WB, F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: EBVCS-5
Application*: F, IP, MC
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: 2G8
Application*: F, E, C
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C2480
Application*: E, WB
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYY-C2479
Application*: IF, F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: CBYY-C2478
Application*: F, IH, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C2477
Application*: F, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2476
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C2475
Application*: E, P
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-C2474
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2473
Application*: F, IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0621
Application*: F, IH, WB
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 691632
Application*: F, MC
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-C0449
Application*: F, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0386
Application*: F, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5000
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0097
Application*: F
Target: FCER2
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: CBFYC-2662
Application*: IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-2661
Application*: EC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2660
Application*: F, N, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0270
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-0021
Application*: E, P
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 7
Application*: IF/C, F
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: 5K250
Application*: F, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 2L6
Application*: WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 2F2
Application*: IH
Target: FCER2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 12K30
Application*: F
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 011
Application*: E
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 1E9
Application*: IH
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 007
Application*: F, IC/IF, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 7H45
Application*: E, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: 5K232
Application*: F, IH, IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5J77
Application*: F, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5F27
Application*: F, IF
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5B5
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5
Application*: E, P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1130
Application*: F, IH
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C23
Application*: F, N, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B6
Application*: WB, IH
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 176
Application*: E
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 160
Application*: P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 14L174
Application*: F, N, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 05
Application*: E, P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3H1136
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 138633
Application*: EC
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-2918
Application*: E, IP, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBXF-0442
Application*: IP, E, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: TS1/18
Application*: P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: T1
Application*: F, IF, C
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP23
Application*: IH
Target: FCER2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP163
Application*: F, P, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: S52
Application*: E, IP, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 9B6
Application*: WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6C2
Application*: P, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5E3
Application*: F
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1468
Application*: WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0457
Application*: IP
Target: FCER2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-0456
Application*: P, WB
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1B12
Application*: P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-0455
Application*: C, P
Target: FCER2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0451
Application*: F, P, IP
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* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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