GPR182
Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin. [provided by RefSeq]
Full Name
G protein-coupled receptor 182
Function
Orphan receptor.
Biological Process
Cell surface receptor signaling pathway Source: ProtInc
Cellular Location
Cell membrane
Topology
Extracellular: 1-57
Helical: 58-79
Cytoplasmic: 80-90
Helical: 91-113
Extracellular: 114-127
Helical: 128-149
Cytoplasmic: 150-170
Helical: 171-193
Extracellular: 194-217
Helical: 218-239
Cytoplasmic: 240-258
Helical: 259-280
Extracellular: 281-299
Helical: 300-320
Cytoplasmic: 321-404
Helical: 58-79
Cytoplasmic: 80-90
Helical: 91-113
Extracellular: 114-127
Helical: 128-149
Cytoplasmic: 150-170
Helical: 171-193
Extracellular: 194-217
Helical: 218-239
Cytoplasmic: 240-258
Helical: 259-280
Extracellular: 281-299
Helical: 300-320
Cytoplasmic: 321-404
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Anti-GPR182 antibodies
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Target: GPR182
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-0454
Application*: E, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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