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HGFAC

This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants.

Full Name

Hgf Activator

Function

Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.

Biological Process

Blood coagulation Source: GO_Central
Proteolysis Source: GO_Central
Zymogen activation Source: GO_Central

Cellular Location

Secreted. Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.

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Anti-HGFAC antibodies

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Mouse Anti-HGFAC Recombinant Antibody (CBFYH-1037) (CBMAB-H1982-FY)

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Target: HGFAC

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYH-1037

Application*: E

Mouse Anti-HGFAC Recombinant Antibody (CBFYH-1036) (CBMAB-H1981-FY)

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Target: HGFAC

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: CBFYH-1036

Application*: WB, IP, IF, E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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