HLA-DQA1
HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq]
Full Name
major histocompatibility complex, class II, DQ alpha 1
Biological Process
Adaptive immune response Source: UniProtKB-KW
Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
Cellular Location
Lysosome membrane; Endosome membrane
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Anti-HLA-DQA1 antibodies
+ Filters

Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1A3
Application*: WB, E
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Dog, Human
Clone: CBFYH-1358
Application*: C, MC, IF
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-1357
Application*: E, PL, WB
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Pig
Clone: CBFYH-1355
Application*: F, IH
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-1354
Application*: E, F, IH, WB
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Pig
Clone: CBFYH-3112
Application*: C, F, FN, IP
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Pig
Clone: CBFYH-3111
Application*: F, C, IP
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BL-IA/6
Application*: WB, P, C, F, IF
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-3110
Application*: F
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-1352
Application*: F, IH
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2HB6
Application*: WB, F, E, IH, IP, R, MC
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-1353
Application*: F, IF
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: WR18
Application*: F, IH, P, FN
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: Tu169
Application*: F
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-3109
Application*: WB, F, E, IH, MC
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Pig
Clone: CBFYH-1351
Application*: F, C, IF
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human, Pig
Clone: CBFYH-3108
Application*: WB, F, IP, MC
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HI118
Application*: F
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: FN81
Application*: C, F
Target: HLA-DQA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-1356
Application*: F, IF, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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