IL34

Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008]
Full Name
Interleukin 34
Function
Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
Biological Process
Inflammatory responseIEA:UniProtKB-KW
Innate immune responseIEA:UniProtKB-KW
Interleukin-34-mediated signaling pathwayManual Assertion Based On ExperimentIDA:ARUK-UCL
Microglial cell proliferationIEA:Ensembl
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of gene expressionIEA:Ensembl
Positive regulation of macrophage chemotaxisManual Assertion Based On ExperimentIDA:ARUK-UCL
Positive regulation of macrophage differentiationManual Assertion Based On ExperimentIDA:CACAO
Positive regulation of macrophage proliferationManual Assertion Based On ExperimentIDA:ARUK-UCL
Positive regulation of MAP kinase activityManual Assertion Based On ExperimentIDA:ARUK-UCL
Positive regulation of monocyte differentiationManual Assertion Based On ExperimentIDA:CACAO
Positive regulation of oligodendrocyte differentiationISS:UniProtKB
Positive regulation of protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of protein tyrosine kinase activityManual Assertion Based On ExperimentIDA:ARUK-UCL
Cellular Location
Secreted
View more

Anti-IL34 antibodies

+ Filters
Loading...

Mouse Anti-IL34 Recombinant Antibody (CBLC224-LY) (CBMAB-C11729-LY)

Go to compareCompare
Target: IL34
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBLC224-LY
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-IL34 Recombinant Antibody (CBT770) (V2LY-0625-LY3290)

Go to compareCompare
Target: IL34
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT770
Application*: WB, IF, IC, F, E
Datasheet SDS

Mouse Anti-IL34 Recombinant Antibody (CBT4600) (V2LY-0625-LY2462)

Go to compareCompare
Target: IL34
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4600
Application*: WB, IC, F
Datasheet SDS

Mouse Anti-IL34 Recombinant Antibody (CBYY-I0987) (CBMAB-I2155-YY)

Go to compareCompare
Target: IL34
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0987
Application*: ED
Datasheet SDS

Rat Anti-IL34 Recombinant Antibody (CBYY-I0739) (CBMAB-I1641-YY)

Go to compareCompare
Target: IL34
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-I0739
Application*: N
Datasheet SDS

Mouse Anti-IL34 (AA 58-217) Recombinant Antibody (578416) (CBMAB-I1403-YY)

Go to compareCompare
Target: IL34
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 578416
Application*: N, IS, MC
Datasheet SDS

Mouse Anti-IL34 Recombinant Antibody (CBYY-I0630) (CBMAB-I1402-YY)

Go to compareCompare
Target: IL34
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0630
Application*: EC
Datasheet SDS

Mouse Anti-IL34 Recombinant Antibody (CBYY-I0210) (CBMAB-I0559-YY)

Go to compareCompare
Target: IL34
Host: Mouse
Antibody Isotype: IgG2a, λ
Specificity: Human
Clone: CBYY-I0210
Application*: ED
Datasheet SDS

Mouse Anti-IL34 Recombinant Antibody (CBYY-I0209) (CBMAB-I0558-YY)

Go to compareCompare
Target: IL34
Host: Mouse
Antibody Isotype: IgG2b, λ
Specificity: Human
Clone: CBYY-I0209
Application*: E
Datasheet SDS

Mouse Anti-IL34 Recombinant Antibody (1D12) (CBMAB-I0557-YY)

Go to compareCompare
Target: IL34
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D12
Application*: E, F, IF, P, WB, IC
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry
Happy Holidays
Happy Holidays close ad