KLK2

This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
Full Name
Kallikrein Related Peptidase 2
Function
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Biological Process
Regulation of systemic arterial blood pressureManual Assertion Based On ExperimentIBA:GO_Central
Zymogen activationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Extracellular exosome
Extracellular region
Secretory granule
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Anti-KLK2 antibodies

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Mouse Anti-KLK2 Recombinant Antibody (A773) (CBMAB-AP4064LY)

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Target: KLK2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A773
Application*: ICC, IHC, IP, WB
Datasheet SDS

Rabbit Anti-KLK2 Recombinant Antibody (CBLY1-122) (CBMAB-K1232-LY)

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Target: KLK2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBLY1-122
Application*: WB, IC/IF
Datasheet SDS

Mouse Anti-KLK2 Recombinant Antibody (5D6) (CBMAB-K1235-LY)

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Target: KLK2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5D6
Application*: IH, WB
Datasheet SDS

Mouse Anti-KLK2 Recombinant Antibody (426723) (CBMAB-K1234-LY)

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Target: KLK2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 426723
Application*: WB, IP, N
Functional Assay
Datasheet SDS

Mouse Anti-KLK2 Recombinant Antibody (3C5) (CBMAB-K1233-LY)

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Target: KLK2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3C5
Application*: E, IF, IP
Datasheet SDS

Mouse Anti-KLK2 Recombinant Antibody (6B7) (CBMAB-K0148-LY)

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Target: KLK2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6B7
Application*: E, P, IC, AP
Datasheet SDS

Mouse Anti-KLK2 Recombinant Antibody (CBT2413) (V2LY-0625-LY1833)

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Target: KLK2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2413
Application*: IH, IC, F
Datasheet SDS

Mouse Anti-KLK2 Recombinant Antibody (CBT4076) (V2LY-0625-LY1776)

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Target: KLK2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4076
Application*: IH, F
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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