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Mouse Anti-KLK2 Recombinant Antibody (3C5) (CBMAB-K1233-LY)

This product is antibody recognizes KLK2. The antibody 3C5 immunoassay techniques such as: ELISA, IF, IP.
See all KLK2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3C5
Antibody Isotype
IgG2b, κ
Application
ELISA, IF, IP

Basic Information

Immunogen
KLK2 (AAH05196, 1 a.a. ~ 262 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 Kda
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Kallikrein Related Peptidase 2
Introduction
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
Entrez Gene ID
3817
UniProt ID
P20151
Alternative Names
Kallikrein Related Peptidase 2; Kallikrein 2; Prostatic; Glandular Kallikrein-1; Tissue Kallikrein-2; HGK-1; Glandular Kallikrein 2;
Function
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Biological Process
Regulation of systemic arterial blood pressureManual Assertion Based On ExperimentIBA:GO_Central
Zymogen activationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Extracellular exosome
Extracellular region
Secretory granule
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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