KRT20
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Full Name
Keratin 20
Function
Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
Biological Process
Apoptotic processIEA:UniProtKB-KW
Cellular response to starvationIEA:Ensembl
Intermediate filament organizationManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of protein secretionIEA:Ensembl
Cellular response to starvationIEA:Ensembl
Intermediate filament organizationManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of protein secretionIEA:Ensembl
Cellular Location
Cytoplasm
PTM
Hyperphosphorylation at Ser-13 occurs during the early stages of apoptosis but becomes less prominent during the later stages. Phosphorylation at Ser-13 also increases in response to stress brought on by cell injury (By similarity).
Proteolytically cleaved by caspases during apoptosis. Cleavage occurs at Asp-228.
Proteolytically cleaved by caspases during apoptosis. Cleavage occurs at Asp-228.
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Anti-KRT20 antibodies
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CompareTarget: KRT20
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: S4
Application*: WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: Ks20.8
Application*: IH, WB
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D9Z1Z
Application*: WB, P, IF, F
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4D10A4
Application*: E, WB, IH
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: A828
Application*: FC, ICC, IF, IHC, IP, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: A827
Application*: IHC, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: A826
Application*: ICC, IF, IHC, WB
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CAP928
Application*: FC, ICC, IF, IHC, IP, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 12
Application*: ELISA, IHC, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: V2-635980
Application*: IHC
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CF263
Application*: ELISA, WB, IHC
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: RM283
Application*: IHC, WB
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CBAb150
Application*: WB, IH, IF, IP
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: MKs20-8
Application*: WB, P, C, IP
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: AT10D8
Application*: E, FC, IF, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5F219
Application*: IH, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: 5F217
Application*: IH, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig, Rat
Clone: 13H232
Application*: FC, IH
Target: KRT20
Host: Rabbit
Specificity: Human
Clone: E19-I
Application*: IH
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Pig
Clone: CBWJC-4046
Application*: C, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: CBWJC-4045
Application*: C, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig, Rat
Clone: CBWJC-4044
Application*: C, E, WB, P
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig, Rat
Clone: CBWJC-4043
Application*: C, IC, F, P
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: Ks 20.8
Application*: P, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4042
Application*: P, F
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-4038
Application*: IH
Target: KRT20
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-4036
Application*: IH
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-4035
Application*: P
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat, Goat, Human, Pig
Clone: CBWJC-2292
Application*: WB, IP, P, C, IC, F
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-1839
Application*: F, FN
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: B9E9
Application*: F, IF
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-2149
Application*: F, IP, C
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-2891
Application*: E, IF, IH, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-0199
Application*: WB, F, E, IF
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5F218
Application*: C, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Pig, Rat
Clone: 5F215
Application*: E, C, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 10B2648
Application*: E, IF, C, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 10D8
Application*: WB, F, E, IC/IF
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: UMAB172
Application*: P
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: UMAB167
Application*: P
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP33
Application*: P
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: Q2
Application*: P, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Pig
Clone: Ks20.3
Application*: IH, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: G1
Application*: IH, WB
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: BV12
Application*: C, P
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6G4
Application*: IH, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6A60
Application*: IH
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5F1
Application*: WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5E6
Application*: P
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5A2
Application*: WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4E5-1F2
Application*: E, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4B4
Application*: IH, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3G1
Application*: P
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A5
Application*: WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2H9
Application*: IH, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2G3-1C8
Application*: IF, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2A2
Application*: IH, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Pig
Clone: 16k207
Application*: IH, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: 16k206
Application*: IH, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 11A1
Application*: P, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 10D5
Application*: WB
Target: KRT20
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLY1-148
Application*: IC, P, IP, WB
Target: KRT20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3089
Application*: IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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