LBP

Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria.
Full Name
LBP
Function
Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria (PubMed:7517398, PubMed:24120359).
Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:7517398, PubMed:24120359).
Biological Process
Acute-phase responseManual Assertion Based On ExperimentIEP:BHF-UCL
Cellular defense responseBy SimilarityISS:BHF-UCL
Cellular response to lipopolysaccharideManual Assertion Based On ExperimentIDA:MGI
Cellular response to lipoteichoic acidManual Assertion Based On ExperimentIDA:MGI
Defense response to Gram-negative bacteriumManual Assertion Based On ExperimentIDA:BHF-UCL
Defense response to Gram-positive bacteriumManual Assertion Based On ExperimentIDA:BHF-UCL
Detection of molecule of bacterial originManual Assertion Based On ExperimentIDA:BHF-UCL
Innate immune responseBy SimilarityISS:BHF-UCL
Leukocyte chemotaxis involved in inflammatory responseIEA:Ensembl
Lipopolysaccharide transportManual Assertion Based On ExperimentIDA:BHF-UCL
Lipopolysaccharide-mediated signaling pathwayManual Assertion Based On ExperimentIDA:BHF-UCL
Macromolecule localizationManual Assertion Based On ExperimentIDA:AgBase
Macrophage activation involved in immune responseManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of tumor necrosis factor productionManual Assertion Based On ExperimentIDA:BHF-UCL
OpsonizationBy SimilarityISS:BHF-UCL
Positive regulation of chemokine productionIEA:Ensembl
Positive regulation of cytolysisManual Assertion Based On ExperimentIDA:AgBase
Positive regulation of interleukin-6 productionManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of interleukin-8 productionManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of macrophage activationManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of neutrophil chemotaxisIEA:Ensembl
Positive regulation of respiratory burst involved in inflammatory responseISS:BHF-UCL
Positive regulation of toll-like receptor 4 signaling pathwayManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of tumor necrosis factor productionManual Assertion Based On ExperimentIDA:BHF-UCL
Response to lipopolysaccharideManual Assertion Based On ExperimentIDA:BHF-UCL
Cellular Location
Secreted
Cytoplasmic granule membrane
Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
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Anti-LBP antibodies

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Mouse Anti-LBP Recombinant Antibody (A869) (CBMAB-AP11379LY)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: A869
Application*: ELISA, IHC, WB
Datasheet SDS

Recombinant Mouse Anti-LBP Antibody (CBHb143) (CBMAB-Hb643-LY)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBHb143
Application*: FuncS, Immuno assays, IP
Datasheet SDS

Recombinant Mouse Anti-LBP Antibody (CBHb142) (CBMAB-Hb642-LY)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle, Dog, Goat, Monkey, Rabbit, Rat, Sheep, Pig
Clone: CBHb142
Application*: FuncS, Immuno assays, IP
Datasheet SDS

Recombinant Rat Anti-LBP Antibody (CBHb019) (CBMAB-Hb640-LY)

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Target: LBP
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBHb019
Application*: FuncS, Immuno assays
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (CBFYA-0091) (CBMAB-X0128-FY)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle, Dog, Goat, Monkey, Rabbit, Rat, Sheep, Pig
Clone: CBFYA-0091
Application*: FN, IA, IP
Datasheet SDS

Rat Anti-LBP Recombinant Antibody (CBFYA-0012) (CBMAB-X0020-FY)

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Target: LBP
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYA-0012
Application*: FN, IA, WB
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (CBYCL-143) (CBMAB-L0044-YC)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYCL-143
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-Lbp Recombinant Antibody (6D528) (CBMAB-L2909-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Rat
Clone: 6D528
Application*: E, WB
Datasheet SDS

Rat Anti-Lbp Recombinant Antibody (9G212) (CBMAB-L2906-YJ)

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Target: Lbp
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 9G212
Application*: WB
Datasheet SDS

Rat Anti-Lbp Recombinant Antibody (CBYJL-2509) (CBMAB-L2905-YJ)

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Target: Lbp
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYJL-2509
Application*: FN, WB
Datasheet SDS

Rat Anti-Lbp Recombinant Antibody (RR433-8) (CBMAB-L2903-YJ)

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Target: Lbp
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: RR433-8
Application*: E, F, WB
Datasheet SDS

Rat Anti-Lbp Recombinant Antibody (CBYJL-2507) (CBMAB-L2902-YJ)

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Target: Lbp
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJL-2507
Application*: E, N
Datasheet SDS

Rat Anti-Lbp Recombinant Antibody (M330-19) (CBMAB-L2901-YJ)

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Target: Lbp
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: M330-19
Application*: E, FN, N, WB
Datasheet SDS

Rat Anti-Lbp Recombinant Antibody (M300-19) (CBMAB-L2900-YJ)

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Target: Lbp
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: M300-19
Application*: WB
Datasheet SDS

Mouse Anti-Lbp Recombinant Antibody (CBYJL-2506) (CBMAB-L2899-YJ)

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Target: Lbp
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYJL-2506
Application*: WB, FN, E
Datasheet SDS

Rat Anti-Lbp Recombinant Antibody (CBYJL-2505) (CBMAB-L2897-YJ)

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Target: Lbp
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYJL-2505
Application*: E
Datasheet SDS

Rat Anti-Lbp Recombinant Antibody (CBYJL-2504) (CBMAB-L2896-YJ)

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Target: Lbp
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJL-2504
Application*: WB, N
Datasheet SDS

Rat Anti-Lbp Recombinant Antibody (CBYJL-2502) (CBMAB-L2894-YJ)

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Target: Lbp
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYJL-2502
Application*: E, N
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (CBYJL-1237) (CBMAB-L0768-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBYJL-1237
Application*: E, WB
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (CBYJL-1236) (CBMAB-L0767-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1236
Application*: E, WB, IH
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (CBYJL-1235) (CBMAB-L0766-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey, Pig, Rat, Goat, Rabbit, Sheep, Cattle
Clone: CBYJL-1235
Application*: IA, IP, FN
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (biG 42) (CBMAB-L0764-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: biG 42
Application*: WB, FN, E, P
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (biG 412) (CBMAB-L0763-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: biG 412
Application*: FN, E
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (9G216) (CBMAB-L0762-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9G216
Application*: E, IP
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (9G215) (CBMAB-L0761-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle, Dog, Goat, Monkey, Pig, Rabbit, Rat, Sheep
Clone: 9G215
Application*: E, IP
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (6G3) (CBMAB-L0760-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle, Dog, Goat, Monkey, Pig, Rabbit, Rat, Sheep
Clone: 6G3
Application*: ED, EC, IP, FN
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (6D531) (CBMAB-L0759-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6D531
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (6D530) (CBMAB-L0758-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6D530
Application*: E
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (4E8) (CBMAB-L0757-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: 4E8
Application*: E, WB
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (CBYJL-1233) (CBMAB-L0756-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1233
Application*: E, WB, IH
Datasheet SDS

Mouse Anti-LBP Recombinant Antibody (1C7) (CBMAB-L0755-YJ)

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Target: LBP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C7
Application*: FN, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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