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LPO

This gene encodes a member of the peroxidase family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Following its secretion from salivary, mammary, and other mucosal glands, this enzyme catalyzes the generation of the antimicrobial substance hypothiocyanous acid. This gene is present in a gene cluster on chromosome 17. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Full Name
LPO
Function
Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (By similarity).
May contribute to airway host defense against infection.
Biological Process
Defense response to bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Detection of chemical stimulus involved in sensory perception of bitter tasteManual Assertion Based On ExperimentIDA:UniProtKB
Hydrogen peroxide catabolic processIEA:UniProtKB-KW
Response to oxidative stress1 PublicationNAS:UniProtKB
Cellular Location
Secreted
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Anti-LPO antibodies

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Mouse Anti-LPO Recombinant Antibody (A920) (CBMAB-AP4185LY)

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Target: LPO
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: A920
Application*: ICC, IHC, IP, WB
Datasheet SDS

Mouse Anti-LPO Recombinant Antibody (CBXS-3730) (CBMAB-S1005-CQ)

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Target: LPO
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Rat
Clone: CBXS-3730
Application*: WB, IC, P, C, E, IP, IF, F
Datasheet SDS

Mouse Anti-LPO Recombinant Antibody (CBYJL-1937) (CBMAB-L1993-YJ)

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Target: LPO
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1937
Application*: WB, IC, P, E
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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