LRRC25

Diseases associated with LRRC25 include Transient Global Amnesia.
Full Name
Leucine Rich Repeat Containing 25
Function
Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specifically with ISG15-associated DDX58 to promote interaction between DDX58 and the autophagic cargo receptor p62/SQSTM1 to mediate DDX58 degradation via selective autophagy (PubMed:29288164).
Plays also a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA.
Biological Process
Membrane
Cytoplasm
Topology
Extracellular: 21-165
Helical: 166-186
Cytoplasmic: 187-305
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Anti-LRRC25 antibodies

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Mouse Anti-LRRC25 Recombinant Antibody (CBYJL-2007) (CBMAB-L2105-YJ)

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Target: LRRC25
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-2007
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-LRRC25 Recombinant Antibody (CBYJL-2006) (CBMAB-L2102-YJ)

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Target: LRRC25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2006
Application*: F, P, WB
Datasheet SDS

Mouse Anti-LRRC25 Recombinant Antibody (1D9) (CBMAB-L2101-YJ)

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Target: LRRC25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D9
Application*: WB, F, IH, IC, IF, P
Datasheet SDS

Mouse Anti-LRRC25 Recombinant Antibody (CBYJL-2005) (CBMAB-L2100-YJ)

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Target: LRRC25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2005
Application*: F, IF, P, WB
Datasheet SDS

Mouse Anti-LRRC25 Recombinant Antibody (CBYJL-2003) (CBMAB-L2098-YJ)

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Target: LRRC25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2003
Application*: F, WB
Datasheet SDS

Mouse Anti-LRRC25 Recombinant Antibody (1B3) (CBMAB-L2097-YJ)

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Target: LRRC25
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1B3
Application*: F, WB
Datasheet SDS

Mouse Anti-LRRC25 Recombinant Antibody (CBYJL-2002) (CBMAB-L2096-YJ)

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Target: LRRC25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2002
Application*: WB, IH, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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