LSAMP

LSAMP is a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. LSAMP may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. LSAMP may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Full Name
LSAMP
Function
Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hippocampal mossy fiber projection (By similarity).
Biological Process
Cell adhesionIEA:UniProtKB-KW
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell membrane
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Anti-LSAMP antibodies

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Mouse Anti-LSAMP Recombinant Antibody (MM0445-3H44) (CBMAB-L2181-YJ)

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Target: LSAMP
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MM0445-3H44
Application*: WB, N
Datasheet SDS

Mouse Anti-LSAMP Recombinant Antibody (2G9) (CBMAB-0138-CN)

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Target: LSAMP
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat, Cattle, Cat, Fish, Human, Mouse
Clone: 2G9
Application*: B, IF, IH, IP, WB
Functional Assay
Datasheet SDS

Human Recombinant LSAMP protein, His Tag (V2LY-0526-LY5386)

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Target: LSAMP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-315
Tag: His Tag
Datasheet SDS

Human Recombinant LSAMP protein, hFc Tag (V2LY-0526-LY5385)

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Target: LSAMP
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-315
Tag: hFc Tag
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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