Human Recombinant LSAMP protein, His Tag (V2LY-0526-LY5386)

Name: Human Recombinant LSAMP protein, His Tag
SKU: V2LY-0526-LY5386
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant LSAMP protein, His Tag consist of Amino Acid: 1-315 and predicts a molecular mass of 33.4 kDa.

Molecule Mass

33.4 kDa

Sequence

Amino Acid: 1-315

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>97% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

LSAMP

Function

Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hippocampal mossy fiber projection (By similarity).

Biological Process

Cell adhesionIEA:UniProtKB-KW
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cell membrane

Xu, X., Gong, C., Wang, Y., Yin, Z., Wang, X., Hu, Y., & Fang, Z. (2023). Bioinformatics analysis and experimental validation identified HMGA2/microRNA-200c-3p/LSAMP/Wnt axis as an immunological factor of patients with colorectal cancer. American Journal of Cancer Research, 13(9), 3898.

Martinez-Monleon, A., Gaarder, J., Djos, A., Kogner, P., & Fransson, S. (2023). Identification of recurrent 3q13. 31 chromosomal rearrangement indicates LSAMP as a tumor suppressor gene in neuroblastoma. International Journal of Oncology, 62(2), 1-11.

Gong, W., Li, Y., Xian, J., Yang, L., Wang, Y., Zhang, X., ... & Qiu, F. (2022). Long non-coding RNA LSAMP-1 is down-regulated in non-small cell lung cancer and predicts a poor prognosis. Cancer Cell International, 22(1), 1-16.

Morgan, D. L., Callais, V. E., Acevedo, M., & Davis, K. B. (2021, August). A potential canary in the coal mine: A critical policy analysis of the Illinois LSAMP during the COVID-19 pandemic. In Frontiers in Education (Vol. 6, p. 668394). Frontiers Media SA.

Preuss, M., Merriweather, S., Avila, J., Butler-Purry, K., Watson, K., Walton, S., ... & Texas A&M University System Louis Stokes Alliance for Minority Participation. (2021, July). The Impacts of Global Research and International Educational Experiences on Texas A&M University System LSAMP Participants. In Frontiers in Education (Vol. 6, p. 674772). Frontiers Media SA.

Chang, C. Y., Wu, K. L., Chang, Y. Y., Liu, Y. W., Huang, Y. C., Jian, S. F., ... & Hsu, Y. L. (2021). The downregulation of LSAMP expression promotes lung cancer progression and is associated with poor survival prognosis. Journal of Personalized Medicine, 11(6), 578.

San Miguel, C., & Gates, A. E. (2021, November). Synergistic Interaction of LSAMP Alliances to Improve the Graduation and Transfer of Community College Students in New Jersey United States. In Frontiers in Education (Vol. 6, p. 679865). Frontiers.

Bregin, A., Kaare, M., Jagomäe, T., Karis, K., Singh, K., Laugus, K., ... & Vasar, E. (2020). Expression and impact of Lsamp neural adhesion molecule in the serotonergic neurotransmission system. Pharmacology Biochemistry and Behavior, 198, 173017.

Hua, X., Liu, Z., Zhou, M., Tian, Y., Zhao, P. P., Pan, W. H., ... & Yu, L. N. (2019). RETRACTED: LSAMP-AS1 binds to microRNA-183–5p to suppress the progression of prostate cancer by up-regulating the tumor suppressor DCN.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant LSAMP protein, hFc Tag (CAT#: V2LY-0526-LY5385)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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