MAZ

MAZ (MYC Associated Zinc Finger Protein) is a Protein Coding gene. Among its related pathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and chromatin binding. An important paralog of this gene is PATZ1.
Full Name
MAZ
Function
Transcriptional regulator, potentially with dual roles in transcription initiation and termination.

Isoform 1:
Binds DNA and functions as a transcriptional activator (PubMed:12270922).

Binds to two G/A-rich sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former (PubMed:1502157).

Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors (PubMed:1502157).

Isoform 2:
Binds DNA and functions as a transcriptional activator (PubMed:12270922).

Inhibits MAZ isoform 1-mediated transcription (PubMed:12270922).

Isoform 3:
Binds DNA and functions as a transcriptional activator.
Biological Process
Negative regulation of apoptotic signaling pathway Source: ARUK-UCL
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Positive regulation of cell migration Source: ARUK-UCL
Positive regulation of cell population proliferation Source: ARUK-UCL
Positive regulation of gene expression Source: ARUK-UCL
Positive regulation of phosphatidylinositol 3-kinase signaling Source: ARUK-UCL
Positive regulation of protein kinase B signaling Source: ARUK-UCL
Positive regulation of transcription, DNA-templated Source: ARUK-UCL
Regulation of transcription by RNA polymerase II Source: GO_Central
Termination of RNA polymerase II transcription Source: UniProtKB
Transcription initiation from RNA polymerase II promoter Source: UniProtKB
Cellular Location
Nucleus
Note: In brains of Alzheimer disease patients, present in a plaque-like structures.
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Anti-MAZ antibodies

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Mouse Anti-MAZ Recombinant Antibody (3D2) (CBMAB-A5322-LY)

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Target: MAZ
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3D2
Application*: WB, E
Datasheet SDS

Mouse Anti-MAZ Recombinant Antibody (3B1) (CBMAB-A5321-LY)

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Target: MAZ
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3B1
Application*: WB, E
Datasheet SDS

Mouse Anti-MAZ Antibody (1D5) (CBMAB-0637-YC)

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Target: MAZ
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1D5
Application*: IP, WB, M
Datasheet SDS

Mouse Anti-MAZ Recombinant Antibody (CBFYM-1779) (CBMAB-M1947-FY)

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Target: MAZ
Host: Mouse
Specificity: Human
Clone: CBFYM-1779
Application*: WB
Datasheet SDS

Mouse Anti-MAZ (AA 1-264) Recombinant Antibody (CBFYM-1778) (CBMAB-M1946-FY)

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Target: MAZ
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-1778
Application*: E, WB
Datasheet SDS

Mouse Anti-MAZ Recombinant Antibody (CBFYM-1777) (CBMAB-M1945-FY)

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Target: MAZ
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-1777
Application*: IP, WB
Datasheet SDS

Mouse Anti-MAZ (AA 332-441) Recombinant Antibody (CBFYM-0785) (CBMAB-M0929-FY)

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Target: MAZ
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-0785
Application*: E, IF, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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