PHYHD1
PHYHD1 has ubiquitous expression in kidney (RPKM 11.6), thyroid (RPKM 9.8) and 23 other tissues.
Full Name
Phytanoyl-CoA Dioxygenase Domain Containing 1
Function
2-oxoglutarate(2OG)-dependent dioxygenase that catalyzes the conversion of 2-oxoglutarate to succinate and CO2 in an iron-dependent manner (PubMed:21530488).
However, does not couple 2OG turnover to the hydroxylation of acyl-coenzyme A derivatives, implying that it is not directly involved in phytanoyl coenzyme-A metabolism (PubMed:21530488).
Does not show detectable activity towards fatty acid CoA thioesters (PubMed:21530488).
Isoform 2
Isoform 2 probably lacks enzyme activity.
Isoform 3
Isoform 3 probably lacks enzyme activity.
However, does not couple 2OG turnover to the hydroxylation of acyl-coenzyme A derivatives, implying that it is not directly involved in phytanoyl coenzyme-A metabolism (PubMed:21530488).
Does not show detectable activity towards fatty acid CoA thioesters (PubMed:21530488).
Isoform 2
Isoform 2 probably lacks enzyme activity.
Isoform 3
Isoform 3 probably lacks enzyme activity.
Anti-PHYHD1 antibodies
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Target: PHYHD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: G-12
Application*: WB, IP, IF, E
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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