PKD1L2

This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Full Name
polycystic kidney disease 1-like 2
Function
May function as an ion-channel regulator. May function as a G-protein-coupled receptor.
Biological Process
Detection of mechanical stimulusManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Extracellular: 18-1344
Helical: 1345-1365
Cytoplasmic: 1366-1552
Helical: 1553-1573
Extracellular: 1574-1594
Helical: 1595-1615
Cytoplasmic: 1616-1818
Helical: 1819-1839
Extracellular: 1840-1865
Helical: 1866-1886
Cytoplasmic: 1887-1943
Helical: 1944-1964
Extracellular: 1965-2143
Helical: 2144-2166
Cytoplasmic: 2167-2182
Helical: 2183-2203
Extracellular: 2204-2218
Helical: 2219-2239
Cytoplasmic: 2240-2270
Helical: 2271-2291
Extracellular: 2292-2312
Helical: 2313-2333
Cytoplasmic: 2334-2377
Helical: 2378-2398
Extracellular: 2399-2459
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Anti-PKD1L2 antibodies

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Mouse Anti-PKD1L2 Recombinant Antibody (CBYC-P397) (CBMAB-P1919-YC)

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Target: PKD1L2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYC-P397
Application*: E, WB
Datasheet SDS

Mouse Anti-PKD1L2 Recombinant Antibody (9G416) (CBMAB-P1918-YC)

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Target: PKD1L2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 9G416
Application*: E, WB
Datasheet SDS

Mouse Anti-PKD1L2 Recombinant Antibody (3F6) (CBMAB-P1917-YC)

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Target: PKD1L2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3F6
Application*: E, WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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