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Mouse Anti-PKD1L2 Recombinant Antibody (3F6) (CBMAB-P1917-YC)

Provided herein is a Mouse monoclonal antibody against Human Polycystin 1 Like 2. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PKD1L2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3F6
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
PKD1L2 (AAH14157, 1-306 aa) full length recombinant protein with GST tag. Immunogen sequence: MGEDSPVAMF SWYLDNTPTE QAEPLPDACR LRGFWPRSLT LLQSNTSTLL LNSSFLQSRG EVIRIRATAL TRHAYGEDTY VISTVPPREV PACTIAPEEG TVLTSFAIFC NASTALGPLE FCFCLESGSC LHCGPEPALP SVYLPLGEEN NDFVLTVVIS ATNRAGDTQQ TQAMAKVALG DTCVEDVAFQ AAVSEKIPTA LQGEGGPEQL LQLAKAVSSM LNQEHESQGS GQSLSIDVRQ KVREHVLGSL SAVTTGLEDV QRVQELAEVL REVTCRSKEL TPSAQGSCMG DSWEGAPPAA HVSHAR
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-306

Target

Full Name
polycystic kidney disease 1-like 2
Introduction
PKD1L2 (Polycystin 1 Like 2 (Gene/Pseudogene)) is a protein coding gene. Diseases associated with PKD1L2 include Polycystic Kidney Disease and Kidney Disease. Among its related pathways are MAPK-Erk Pathway. Gene Ontology annotations related to this gene include calcium ion binding and ion channel activity. An important paralog of the gene is PKDREJ.
Entrez Gene ID
114780
UniProt ID
Q7Z442
Alternative Names
PC1L2
Function
May function as an ion-channel regulator. May function as a G-protein-coupled receptor.
Biological Process
Detection of mechanical stimulusManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Extracellular: 18-1344
Helical: 1345-1365
Cytoplasmic: 1366-1552
Helical: 1553-1573
Extracellular: 1574-1594
Helical: 1595-1615
Cytoplasmic: 1616-1818
Helical: 1819-1839
Extracellular: 1840-1865
Helical: 1866-1886
Cytoplasmic: 1887-1943
Helical: 1944-1964
Extracellular: 1965-2143
Helical: 2144-2166
Cytoplasmic: 2167-2182
Helical: 2183-2203
Extracellular: 2204-2218
Helical: 2219-2239
Cytoplasmic: 2240-2270
Helical: 2271-2291
Extracellular: 2292-2312
Helical: 2313-2333
Cytoplasmic: 2334-2377
Helical: 2378-2398
Extracellular: 2399-2459
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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