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PLCB3

PLCB3 is a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction.

Full Name

Phospholipase C beta 3

Function

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

Biological Process

G protein-coupled receptor signaling pathwayTAS:Reactome
Lipid catabolic processIEA:UniProtKB-KW
Phosphatidylinositol metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Phosphatidylinositol-mediated signalingManual Assertion Based On ExperimentIBA:GO_Central
Regulation of systemic arterial blood pressureManual Assertion Based On ExperimentIDA:MGI

Cellular Location

Cytoplasm
Membrane
Nucleus
And particulate fractions.

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Anti-PLCB3 antibodies

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Rabbit Anti-PLCB3 Recombinant Antibody (D9D6S) (CBMAB-P2049-YC)

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Target: PLCB3

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat, Monkey, Cattle, Dog

Clone: D9D6S

Application*: WB

Human PLCB3 ELISA Kit (V2LY-0626-LY4291)

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Target: PLCB3

Sensitivity: 0.0097 ng/mL

Detection Range: 0.02-4.5 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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