PPP1R1B

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Full Name
protein phosphatase 1 regulatory inhibitor subunit 1B
Function
Inhibitor of protein-phosphatase 1.
Biological Process
Behavioral response to cocaineIEA:Ensembl
Cellular response to cocaineIEA:Ensembl
Intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Locomotory behaviorIEA:Ensembl
Negative regulation of female receptivityIEA:Ensembl
Negative regulation of phosphoprotein phosphatase activityManual Assertion Based On ExperimentIDA:CAFA
Response to amphetamineIEA:Ensembl
Response to morphineIEA:Ensembl
Signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Transcription, DNA-templatedIEA:Ensembl
Visual learningIEA:Ensembl
Cellular Location
Cytoplasm
PTM
Dopamine- and cyclic AMP-regulated neuronal phosphoprotein.
Phosphorylation of Thr-34 is required for activity.
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Anti-PPP1R1B antibodies

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Rabbit Anti-PPP1R1B Monoclonal Antibody (EP720Y) (CBMAB-0981-YC)

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Target: PPP1R1B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Pig
Clone: EP720Y
Application*: F, IC, IF, C, P, IP, WB
Datasheet SDS

Mouse Anti-PPP1R1B Recombinant Antibody (1A3) (CBMAB-A6967-LY)

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Target: PPP1R1B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1A3
Application*: WB, E
Datasheet SDS

Mouse Anti-PPP1R1B Recombinant Antibody (3G11) (CBMAB-P2613-YC)

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Target: PPP1R1B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3G11
Application*: E, WB
Datasheet SDS

Rat Anti-PPP1R1B Recombinant Antibody (141515) (CBMAB-P2611-YC)

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Target: PPP1R1B
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 141515
Application*: P, WB
Datasheet SDS

Mouse Anti-Ppp1r1b Recombinant Antibody (15/DARPP-32) (CBMAB-D2195-YC)

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Target: PPP1R1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Rat
Clone: 15/DARPP-32
Application*: WB, IF
Datasheet SDS

Rabbit Anti-PPP1R1B Recombinant Antibody (19A3) (CBMAB-D2194-YC)

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Target: PPP1R1B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 19A3
Application*: WB, IP, P, IF
Datasheet SDS

Rat Anti-PPP1R1B Recombinant Antibody (7H163) (CBMAB-D0240-YC)

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Target: PPP1R1B
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse, Rat
Clone: 7H163
Application*: E, WB, IH
Datasheet SDS

Rabbit Anti-PPP1R1B Recombinant Antibody (7H17) (CBMAB-D0238-YC)

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Target: PPP1R1B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: 7H17
Application*: WB, IP, IH, IF
Datasheet SDS

Rabbit Anti-PPP1R1B Recombinant Antibody (K.935.4) (CBMAB-D0237-YC)

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Target: PPP1R1B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: K.935.4
Application*: IF, P, IP, WB
Datasheet SDS

Rabbit Anti-PPP1R1B Recombinant Antibody (CBYCD-151) (CBMAB-D0235-YC)

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Target: PPP1R1B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Pig
Clone: CBYCD-151
Application*: WB, IP, P, C, IC, F, IF
Datasheet SDS

Mouse Anti-PPP1R1B Recombinant Antibody (2G6D9) (CBMAB-D0234-YC)

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Target: PPP1R1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2G6D9
Application*: WB, F, E
Datasheet SDS

Mouse Anti-PPP1R1B Recombinant Antibody (2A4G9) (CBMAB-D0233-YC)

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Target: PPP1R1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A4G9
Application*: WB, E
Datasheet SDS

Mouse Anti-PPP1R1B Monoclonal Antibody (2A4G9) (CBMAB-0985-YC)

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Target: PPP1R1B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2A4G9
Application*: E, WB
Datasheet SDS

Mouse Anti-PPP1R1B Monoclonal Antibody (2G6D9) (CBMAB-0984-YC)

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Target: PPP1R1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2G6D9
Application*: E, F, WB
Datasheet SDS

Rabbit Anti-PPP1R1B Monoclonal Antibody (K.935.4) (CBMAB-0983-YC)

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Target: PPP1R1B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: K.935.4
Application*: IF, P, IP, WB
Datasheet SDS

Rabbit Anti-PPP1R1B Monoclonal Antibody (EP721Y) (CBMAB-0982-YC)

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Target: PPP1R1B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EP721Y
Application*: IC, IF, P, IP, WB
Datasheet SDS

Mouse Anti-PPP1R1B Recombinant Antibody (CBT2003) (V2LY-0625-LY30)

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Target: PPP1R1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2003
Application*: WB
Datasheet SDS

Mouse Anti-PPP1R1B Recombinant Antibody (CBT4147) (V2LY-0625-LY111)

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Target: PPP1R1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4147
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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