RAB11FIP1

This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]

RAB11 Family Interacting Protein 1

A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis.

Biological Process negative regulation of adiponectin secretionManual Assertion Based On ExperimentIDA:CACAO
Biological Process protein transportIEA:UniProtKB-KW
Biological Process regulated exocytosisManual Assertion Based On ExperimentIBA:GO_Central

Recycling endosome
Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC).
Isoform 2
Cytoplasmic vesicle, phagosome membrane
Membrane-bound (isoform 2). Colocalizes with Rab11A at phagosomes (isoform 2).