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Mouse Anti-RAB11FIP1 Recombinant Antibody (CBXF-2478) (CBMAB-F0094-CQ)

This product is a mouse antibody that recognizes RAB11FIP1. The antibody CBXF-2478 can be used for immunoassay techniques such as: WB, FC, ELISA, IHC, IHC-P, ICC, CyTOF.
See all RAB11FIP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBXF-2478
Antibody Isotype
IgG
Application
WB, FC, ELISA, IHC, IHC-P, ICC, CyTOF

Basic Information

Immunogen
Purified recombinant fragment of human RAB11FIP1 (AA: 130-271) expressed in E. coli
Specificity
Human, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
RAB11 Family Interacting Protein 1
Introduction
This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome.
Entrez Gene ID
Human80223
Mouse75767
UniProt ID
HumanQ6WKZ4
MouseQ9D620
Alternative Names
RAB11 Family Interacting Protein 1; RAB11 Family Interacting Protein 1 (Class I); Rab11-FIP1; RCP; Rab11 Family-Interacting Protein 1; Rab-Interacting Recycling Protein; RAB11 Coupling Protein;
Function
A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis.
Biological Process
Biological Process negative regulation of adiponectin secretionManual Assertion Based On ExperimentIDA:CACAO
Biological Process protein transportIEA:UniProtKB-KW
Biological Process regulated exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Recycling endosome
Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC).
Isoform 2
Cytoplasmic vesicle, phagosome membrane
Membrane-bound (isoform 2). Colocalizes with Rab11A at phagosomes (isoform 2).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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