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Rabbit Anti-RAB11FIP1 Recombinant Antibody (D9D8P) (CBMAB-R0698-CN)

This product is a Rabbit antibody that recognizes RAB11FIP1. The antibody D9D8P can be used for immunoassay techniques such as: WB, IP, IF.
See all RAB11FIP1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Monkey
Clone
D9D8P
Application
WB, IP, IF

Basic Information

Specificity
Human, Mouse, Monkey
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
RAB11 Family Interacting Protein 1
Introduction
This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]
Entrez Gene ID
Human80223
Mouse75767
Monkey698884
UniProt ID
HumanQ6WKZ4
MouseQ9D620
MonkeyH9F397
Alternative Names
RAB11 Family Interacting Protein 1; RAB11 Family Interacting Protein 1 (Class I); Rab11-FIP1; RCP; Rab11 Family-Interacting Protein 1; Rab-Interacting Recycling Protein; RAB11 Coupling Protein;
Function
A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis.
Biological Process
Biological Process negative regulation of adiponectin secretionManual Assertion Based On ExperimentIDA:CACAO
Biological Process protein transportIEA:UniProtKB-KW
Biological Process regulated exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Recycling endosome
Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC).
Isoform 2
Cytoplasmic vesicle, phagosome membrane
Membrane-bound (isoform 2). Colocalizes with Rab11A at phagosomes (isoform 2).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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